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Ministry of Transport: Four measures to prevent and control the epidemic situation in Spring Festival travel rush and provide services.

  People’s Daily Online, Beijing, January 30 (Reporter Lu Jing) On January 30, the joint prevention and control mechanism of the State Council held a press conference. Han Jinghua, Deputy Director of the Transport Services Department of the Ministry of Transport, attended the conference and answered questions from reporters.

  This year, the passenger flow in Spring Festival travel rush has increased substantially. How can the Ministry of Transport do a good job in epidemic prevention and control and service? Han Jinghua introduced that there are four specific measures as follows:

  The first is to formulate and implement epidemic prevention guidelines and refine the prevention and control measures of epidemic situation. According to the requirements of "Class B Management" and the characteristics of passenger flow in Spring Festival travel rush, the epidemic prevention and control guidelines for comprehensive transportation in Spring Festival travel rush and Covid-19 were formulated, and 14 epidemic prevention measures were defined in four aspects: disinfection and ventilation of stations and means of transport, protection of employees, publicity and guidance, and emergency response. Strengthen dispatch and supervision, guide all localities to strictly implement the requirements of the guidelines, disinfect and ventilate the passenger contact areas, facilities, equipment and means of transportation in the station, strengthen the health monitoring and protection of employees, and stop operations as soon as symptoms appear to ensure the safety of transportation and epidemic prevention.

  The second is to optimize transportation service measures to minimize the risk of infection. Actively provide non-contact services such as online ticket purchase, e-ticket and self-service ticket inspection to reduce unnecessary personnel contact. Strengthen the passenger flow organization of passenger stations, guide the public to queue up in an orderly manner, disperse and wait for passengers, and reduce the concentration of people. Increase the input of transportation capacity during peak hours, operate "point-to-point" chartered cars and increase night buses according to the needs of the masses, strengthen the connection between different modes of transportation, improve the transportation service capacity, and reduce the gathering of people and long waiting. At the same time, some key passenger stations have also prepared necessary epidemic prevention materials such as antipyretics and thermometers to deal with emergencies.

  The third is to organize supervision and inspection and implement the main responsibility of epidemic prevention and control. In order to implement the epidemic prevention measures of transportation, transportation departments at all levels have carried out various forms of comprehensive and special inspections. Before the Spring Festival, the Ministry of Transport, together with relevant departments, went to 13 provinces to carry out supervision and inspection, and urged transport operators to strictly implement epidemic prevention and control measures such as disinfection and ventilation of passenger stations and vehicles, transportation organization and personnel protection, and resolutely guard against the spread of the epidemic through transportation.

  The fourth is to strengthen epidemic prevention propaganda and guide the masses to travel rationally at the wrong peak. Make full use of service guarantee windows such as "cars, boats, airplanes, roads, ports and stations" and media channels such as television, radio and internet, strengthen epidemic prevention propaganda, release travel information in time, guide the public to travel rationally and avoid peaks, remind passengers to avoid taking public transport when they are sick, wear masks regularly throughout the trip, actively reduce gathering, and be the first person responsible for their own health.

  In addition, Han Jinghua stressed that at present, it is at the peak of returning after the holiday, reminding the majority of passengers that in order to be safe and healthy, they should wear masks all the way in the process of entering and leaving the passenger station and taking public transportation, and work together to prevent and control the traffic epidemic.

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Foreign trade "new three" continues to be hot, industrial upgrading tamps down the cornerstone of development

  Since the beginning of this year, with the combination of macro-control policies, the main economic indicators have stabilized and rebounded obviously. During this period, relying on the strong industrial chain supply chain production advantages and super-large-scale market advantages, some emerging fields have made eye-catching development performance. From now on, People’s Daily launched a series of reports on "Where did the economic highlights come from?".

Domestic new energy vehicles are loaded and exported at Nansha automobile port. Photo courtesy of Guangzhou Port Group

  Domestic new energy vehicles are loaded and exported at Nansha automobile port. Photo courtesy of Guangzhou Port Group

  In November, in Nansha Seaport, Guangzhou, with dense routes, brand-new domestic new energy vehicles were driven to the loading and unloading area at the front of the terminal in an orderly manner and sent to overseas markets such as Southeast Asia by foreign trade ro-ro ships. After packing in Dongguan, batches of lithium battery packs set off on the whistle of the China-Europe train and rushed to the "Belt and Road" country … …

  Since the beginning of this year, the export of "new three" products such as electric manned vehicles, lithium-ion batteries and solar cells has maintained a rapid growth momentum. In the first three quarters, the total export of "new three samples" increased by 41.7% year-on-year, accounting for 1.3 percentage points of China’s export. At the 134th Canton Fair held not long ago, the scale of new energy exhibition area increased by 172% compared with the previous one, which further helped the export of "new three products" and promoted the development of emerging advantageous industries.

  Foreign trade is an important window to observe a country’s economy. From "Made in China" to "Made in China", and from "old three kinds" to "new three kinds", the upgrading trend of China’s foreign trade export products is becoming more and more obvious, which is not only the embodiment of the continuous optimization of foreign trade structure, but also the true portrayal of new kinetic energy promoting high-quality economic development.

  Why have the "new three kinds" of foreign trade become hot in recent two years? Experts said that this is not an accident, but the harvest of China’s comprehensive layout and deep cultivation in related industries for many years.

  Xu Haidong, deputy chief engineer of China Automobile Industry Association, pointed out that in recent years, China has led the green and low-carbon transformation, applied the latest iterative technology and continuously improved its research and development capabilities. The "new three samples" export has produced excellent report cards, which fully reflects the technological innovation advantages brought by China’s increasingly complete industrial chain.

  A complete industrial chain supply chain system is a solid cornerstone of industrial development.

  In the Yangtze River Delta region of China, through the coordinated development of industrial clusters, a new energy automobile factory can solve the supply of necessary supporting parts within four hours’ drive, forming a "four-hour industrial circle" that embodies the characteristics of modern industrial system. At present, China’s green and low-carbon transportation system has been accelerated, and more than half of the world’s new energy vehicles are driving in China, ranking first in the world in production and sales for eight consecutive years. The continuous and complete industrial chain has provided a solid and powerful support for the new energy automobile industry to maintain its leading development momentum.

  In the view of Liu Wenqiang, Party Secretary and Vice President of China Electronic Information Industry Development Research Institute, the main supporting factor behind the high growth of "new three kinds" exports is the industrial competitiveness precipitated by China’s manufacturing industry for many years. "China’s manufacturing system is constantly improving, technological innovation is constantly improving, manufacturing capacity is outstanding, and the industrial chain is complete and resilient, which all have certain leading advantages in the world." Liu Wenqiang said.

  Taking the photovoltaic industry as an example, in recent years, China’s photovoltaic industry has formed the most complete industrial supporting environment and supply chain system in the world, from upstream silicon material technology research and development, midstream component manufacturing and downstream power station development, with a total industrial output value exceeding 1.2 trillion yuan.

  In the first three quarters of this year, the photovoltaic industry continued to achieve rapid development. From the manufacturing side, the output of polysilicon, silicon wafers, battery chips, components and other major manufacturing links increased by over 70% year-on-year; From the perspective of import and export, the export volume of silicon wafers, batteries and components increased by 88.3%, 74.3% and 33% respectively.

  The leading momentum is hard-won. Experts pointed out that we still have to make a lot of "hard work" to maintain the vitality and advantages of the new kinetic energy of the industry for a long time.

  On September 5, the Ministry of Industry and Information Technology put forward various measures to promote China’s industrial enterprises to adhere to innovation and promote system upgrading at the "press conference on the theme of steady industrial growth" — —

  Strengthen quality brand building, promote supply-side innovation, and create demand with high-quality supply; Strengthen the overall planning of the "14 th Five-Year Plan" in the field of industry and information technology, and promote industrial investment funds to increase investment in manufacturing; Continue to do a good job in China’s industrial transfer and development docking activities, and promote qualified projects to be put into production as soon as possible to achieve results; Guide enterprises to expand the international market according to local conditions, and further tap the export potential while consolidating the export of key industrial products.

  "I believe that with the continuous implementation of the above-mentioned series of effective measures, ‘ Three new samples ’ The new kinetic energy of the industry that leads will surely explode with greater development vitality. " Xu Haidong believes that the export growth of the "new three products" is expected to continue in the future: from the outside, the global attention to new energy and green low-carbon development is gradually increasing, and the international market demand for "new three products" is still very strong; Domestically, supported by the advantages of industrial chain and policy environment, the supply of "new three kinds" products still has great advantages on a global scale.

  Liu Wenqiang said that enterprises should persist in innovation and continuously improve their technical content and product quality, so as to actively adapt to the external environment, cope with risk challenges and further release new industrial kinetic energy. On the one hand, it is necessary to strengthen the layout of basic forward-looking technologies and explore new innovation models. Encourage the "chain owner" enterprises in the industrial chain to take the lead, unite upstream and downstream partners, universities and research institutions to build an innovation platform, and focus on tackling common key technical problems; On the other hand, it is necessary to optimize the allocation of resource elements, guide the coordinated development of industrial clusters, coordinate the differentiated and characteristic layout as a whole, and promote the upgrading and efficiency of industries.

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Enterprise’s Character: An Analysis of Ruixun’s Financial Fraud from the Perspective of ESG

  On February 1st, 2020, Muddy Waters Research published an 89-page research report, pointing out that Luckin Coffee (hereinafter referred to as "Ruixing"), a Chinese stock company listed on Nasdaq, was fabricating its financial and operational data, saying that "in the third quarter of 2019 and the fourth quarter of 2019, the daily consumption of goods in each store was exaggerated by at least 69% and 88% respectively". On April 2, Ruixing admitted that the fictitious transaction amount was about 2.2 billion yuan, and then its share price plummeted by 80%, and trading was suspended several times during the session. On April 3rd, China Securities Regulatory Commission issued an announcement strongly condemning the financial fraud of Ruixing, saying that it would strictly follow the relevant arrangements of international securities regulatory cooperation, check the relevant situation according to law, resolutely crack down on securities fraud and effectively protect the rights and interests of investors.


  As the old saying goes, "If you don’t keep your word, you won’t stand". The Ruixing incident has had a very serious negative impact on the international reputation of China enterprises, and some investors even have a natural sense of rejection of China Stock Exchange, indirectly contributing to the phenomenon that "bad money drives out good money" in the market recently, affecting employees, supply chains, customers and other stakeholders. From the perspective of ESG, this paper will analyze the various contents of "Ruixing Incident" in detail, and provide warning and reference for regulators, enterprises and investors.


  First, the background of the "Luckin Coffee" financial fraud incident


  (A) the seriousness and negative impact of the Ruixing incident


  1. The credibility of enterprise data in China was questioned.


  The seriousness of financial information fraud is self-evident. This time, Luckin Coffee directly thundered in the US financial market, crushing the international reputation accumulated by China Stock Exchange in one fell swoop and igniting the trust crisis of China enterprises. In the eyes of more overseas investors, they may not know that Ruixing is a case, nor do they know the industry in which Ruixing is located and the business model adopted, but they will stick to the stereotype that this is a China enterprise and a China enterprise with financial fraud as high as 2.2 billion yuan. So how can we judge whether the data of other China enterprises are equally doubtful?


  Based on the principle of information asymmetry, foreign investors will not have a natural trust in China Stock Exchange. On the contrary, China enterprises have to make great efforts to win the favor of investors bit by bit through long-term stable performance level and good corporate governance mechanism. However, Luckin Coffee unscrupulously fabricated a huge transaction amount of up to 2.2 billion yuan, ignoring the law and discipline, and directly sent an extremely negative signal: the credibility of data is insufficient. From good to good, from evil to collapse. The far-reaching impact of "Ruixun Incident" can never be remedied overnight, and the difficulties of China Stock Exchange will only worsen. Even if high-quality enterprises take out powerful third-party forensic materials to endorse and try to prove the authenticity, integrity and effectiveness of their own data, they still need to face the trust stain of "Ruixun Incident".


  At the same time, among the top ten institutional shareholders of Ruixing, there are many famous investment institutions such as Bank of America, UBS and Melvin Capital Management Company. Among the funds with heavy positions in Luckin Coffee, there are also internationally renowned asset management companies such as American Funds and BlackRock. The occurrence of this "Ruixing incident" will seriously affect the trust of investors in top asset management institutions in China’s corporate data, leading to incalculable consequences.


  2. Directly infringe upon the basic rights and interests of stakeholders.


  First, it will directly infringe on the basic rights and interests of employees and consumers. By December 31, 2019, there were 4,507 directly operated stores in Luckin Coffee with tens of thousands of employees. The follow-up progress of the "Ruixing incident" is not optimistic. If it really involves delisting, insolvency or even bankruptcy liquidation, employees will be forced to bear the risk of unemployment at first, and consumers who have prepaid money (such as recharging) will find it more difficult to recover losses. In addition, on the moral and emotional level, Ruixing directly trampled on the trust of employees and consumers, causing bad social impact.


  Second, it will endanger the basic rights and interests of investors. Wind data shows that by the end of 2019, there were 158 institutional investors holding Luckin Coffee shares, with a total of 460 million shares, accounting for 23.93% of institutional shares. At the same time, as shown in Table 1, as of April 8, 2020, the total market value of Ruixing has shrunk from 66 billion yuan at the end of 2019 to 7.84 billion yuan, a cliff-like decrease of 88.12%; The market value of circulation fell to 3 billion yuan, less than one-third of the end of 2019.


企业的品格:从ESG角度分析瑞幸财务造假事件


  Third, the corresponding supply chain enterprises will be hit hard. Luckin Coffee’s supply chain includes Ruixing Baking (Tianjin) Co., Ltd., which was established in May 2019 with a registered capital of 200 million yuan, Swiss coffee maker Shelley and franca, syrup supplier Fabry, dairy supplier Fonterra, coffee raw bean trader Mitsui Products and baking factory Taiwan Province Yuanyou, and Louis Dafu, one of the four major grain merchants. There are a lot of payables in the transaction between suppliers and Ruixing. Judging from the sales scale and the number of stores in Luckin Coffee, there is a risk that the payment cannot be settled in time and comprehensively. "Ruixing incident" not only affects the construction of good supply chain relations, but also directly brings huge financial risks to suppliers. Once Ruixun’s financial fraud event turns into a debt crisis, it will be difficult for suppliers to directly circulate customized equipment and goods in the market (such as Ruixun’s customized coffee machine and product packaging, etc.), which may involve huge economic losses.


  (B) the basic logic of financial fraud in the Ruixing incident


  1. Ruixun’s information disclosure is seriously distorted, and the financial audit mechanism fails.


  From the second quarter to the fourth quarter of 2019, Ruixing executives and some employees forged transactions worth about 2.2 billion yuan. As of April 8, 2020, according to the quarterly financial information of Ruixun in Wind database, the total operating income of Ruixun in the second and third quarters of 2019 was 910 million yuan and 1.54 billion yuan respectively, and the financial report in the fourth quarter has not been released. The market expects the revenue in the fourth quarter of 2019 to be between 2.1 billion and 2.2 billion yuan. Therefore, the proportion of financial fraud is conservatively estimated to be as high as 48.35%.


  Ruixun’s financial fraud method is still in the investigation stage, but according to the five conclusive evidences and six dangerous signals listed in the "fraud" section of the Muddy Water Report, Ruixun’s financial fraud methods may include, but are not limited to: increasing the pick-up number out of thin air by means of "jumping the number of the pick-up code" and blocking the direct correlation between the pick-up code and the daily order volume, thus increasing the online order volume by 72%; Providing free beverage coupons to existing users to invisibly increase the promotion, while falsely claiming that the proportion of free items continues to decline, and the actual sales price has increased by 9% (accounting for the proportion of listed prices); In the third quarter of 2019, the advertising expenditure was exaggerated by 336 million yuan, and there is reason to suspect that it was used for fraudulent income and forged store profits. Ruixing’s financial information disclosure is seriously distorted, and it is difficult to identify it through standardized audit processes and means. Specifically, Muddy Waters Company used a total of 1,510 employees, including 92 full-time employees and 1,418 part-time employees, to visit 981 stores in Luckin Coffee, collect a total of 25,843 shopping receipts, and shoot 11,260 hours of store videos. The time and economic costs are huge, which can never be completed by the basic financial audit mechanism.


  At present, there is no conclusion as to whether Ernst & Young Huaming Certified Public Accountants, which issued the audit report for Ruixing, should bear the responsibility. However, even if the accounting firm has indeed properly fulfilled its expert obligations, the occurrence of the "Ruixing incident" has revealed the natural shortcomings of financial auditing in the face of human fraud and fraud.


  2. Ruixun’s internal control has failed and there are major defects.


  Luckin Coffee’s 2019 prospectus (Form F-1 of the US Securities and Exchange Commission) shows that the audit results of the consolidated financial statements as of December 31, 2018 show that Rui survived two "major defects" in financial and internal control. According to the definition of the standards formulated by the Accounting Oversight Board (PCAOB) of listed companies in the United States, "material defect" refers to a defect or combination of defects in the internal control of financial reports, and there is the possibility that the material misstatement of annual or interim financial statements has not been reasonably and timely prevented or discovered. Ruixing disclosed that it lacked sufficient accounting and financial reporting personnel, necessary knowledge and experience in applying US GAAP and the rules of the Securities and Exchange Commission (SEC), and financial reporting procedures that met US GAAP and the requirements of the Securities and Exchange Commission (SEC).


  Ruixing is a listed Chinese stock company in the United States, which is bound by the Sarbanes-Oxley Act of 2002. Article 404 clearly requires the management to undertake the responsibility of establishing and maintaining a proper internal control structure, and requires listed companies to provide internal control reports and internal control evaluation reports in their annual reports. At present, Ruixing has not disclosed the 2019 financial report and internal control report, but the latest information still cannot confirm that the effectiveness of its internal control has been convincingly improved.


  3. Ruixun’s "investor protection" system is lacking.


  The way of stock pledge financing is to use the securities held as collateral to obtain loans, without the need for management to sell shares directly. However, when the value of pledged shares falls, the lending institution has the right to ask the borrower to provide more cash or collateral, and may ask for compulsory liquidation when the borrower fails to perform. In the face of financial risks, large-scale stock pledge will cause the stock price of the corresponding securities to plummet, which will harm the remaining investors in the market and form a negative cycle, so it is a key negative danger signal for investors. The research report of Muddy Waters shows that the management of Ruixun has mortgaged nearly 50% of its shares as loan collateral (61 million ADS), accounting for 24% of the total shares of Ruixun, even exceeding the total shares (51 million ADS) placed by Ruixun in May 2019 and January 2020, so investors will face serious financial risks.


  Second, the ESG performance level of Luckin Coffee


  (1) Environment (e)


  Ruixing is a new retail professional coffee operator who mainly sells coffee and related drinks, so its production and business operation objects mainly include the whole process of sales and service of coffee drinks. According to the data of American Professional Coffee Association (SCAA), the water polluted by wastewater in the process of coffee water grinding is 40 times as much as that wasted by urban sewers on average. Ruixing has not released a separate social responsibility report, nor has it disclosed its own treatment and recycling methods of sewage and wastewater on the official website. At the same time, the product packaging of coffee catering service industry is also polluted and wasted. As a new retail coffee operator, Ruixing’s take-away service involves more packaging materials than the average catering service. Even if environmental protection kraft paper packaging bags are used, coffee cups still have problems such as degradation and difficulty in direct recycling. At present, there is no direct evidence that it has been punished by the environmental protection department, but the lack of information about the environmental level of Ruixing makes it impossible to carry out relevant environmental assessment, and the real situation is in doubt.


  (2) society (s)


  One of the most important points in Ruixun’s business model and brand proposition is to change the coffee consumption experience with the new retail model. Therefore, Ruixun believes in standardized processes and operating mechanisms more than paying attention to the practical needs of employees, uniting corporate cohesion and shaping common values. Ruixing does not encourage or advocate the communication between employees and customers, but only provides the online purchase method of ordering. With fully automatic coffee machine, each order must be completed within 2 minutes, and the completion process of each preset program needs to be supervised by a special person in the monitoring center. Any illegal operation and delay in operation time will be reflected in the performance evaluation process linked to salary and counted by the digital management system. At the same time, even a number of stores will be arranged in the same community, and there is a competitive situation. On the whole, Ruixun’s social development is not sustainable, and its employees have no sense of belonging and consumers’ loyalty is low, which is directly reflected in the fact that Ruixun still needs to take great efforts to promote sales.


  (C) Corporate Governance (G)


  In terms of organizational structure, Luckin Coffee and Chairman CAR Inc. are both Lu Zhengyao, and its subsidiary, Hydrogen Dynamics Yiwei, reached a strategic cooperation with Luckin Coffee in all-media integration in 2018, involving significant related party transactions. According to the news of Bloomberg on the evening of April 6, Bronstein, Gewirtz & Grossman, a professional class action service agency, announced that it had filed a class action lawsuit against Ruixing and its senior management on behalf of investors, aiming to demand the defendant to compensate for the alleged violation of the Securities Exchange Act of 1934. At the same time, the fourth paragraph of Article 2 of the new Securities Law, which came into effect on March 1, 2020, clearly requires that "securities issuance and trading activities outside People’s Republic of China (PRC) disrupt the market order in People’s Republic of China (PRC) and damage the legitimate rights and interests of domestic investors, they shall be dealt with and investigated for legal responsibility in accordance with the relevant provisions of this Law", and a serious condemnation announcement will be issued for the Ruixing incident, which will resolutely crack down on fraud. Ruixing’s corporate management is bad, its internal control is seriously flawed, and its information disclosure is seriously distorted. The financial fraud of senior executives has involved criminal responsibility including fraud, and it will directly face the early warning risk of delisting.


  Third, the ESG logic behind the Ruixing incident


  (A) the relevance of ESG and financial performance


  ESG integrates environmental, social and governance factors, which can comprehensively reflect the non-financial performance of enterprises and evaluate the long-term sustainable development ability of enterprises. A large number of domestic and foreign literature studies have shown that ESG is related to company valuation, stock returns, financing costs and other factors related to company quality. Cohen et al. (1997) compared the environmental performance and financial performance of manufacturing companies in the S&P500 index, and found that the environmental performance is positively correlated with the intangible assets value of listed companies. This study shows that good environmental performance can increase the valuation of intangible assets of listed companies. In addition to a single environmental factor, Brammer & Millington(2008) discussed the relationship between corporate social performance (CSP) and corporate financial performance (), and found that in the short term, companies with poor CSP performance have better financial performance; But in the long run, companies with good CSP performance have better financial performance.


  In 2018, the Green Finance International Research Institute of Central University of Finance and Economics published two research results, namely, Research on the Correlation between ESG Performance of Listed Companies in China and Corporate Performance, and Research on the Correlation between ESG Performance of Listed Companies in China and Corporate Default Risk, which is also one of the important achievements of the China-UK Green Finance Working Group. It is found that ESG performance in manufacturing industry is positively correlated with the company’s P/B ratio and P/E ratio, while ESG performance is negatively correlated with stock risk, which is particularly significant in manufacturing industry. In terms of ESG and bond default rate, it is found that the higher the ESG level, the lower the probability of corporate bond default or downgrade, and the higher the ESG level, the higher the corporate bond yield.


  At the same time, some scholars suggest that ESG performance has a negative correlation with the company’s downside risks. Koehler and Hespenheide(2013) believe that ESG problems will lead to corporate crises, and those companies that are clearly prepared to deal with ESG shocks can better mitigate short-term and long-term downside risks. Hoepner et al. (2018) found that ESG problems can benefit shareholders by reducing the company’s downside risks.


  (B) ESG is a key indicator to measure the credit quality of enterprises.


  If the financial report maps the current credit ability of the enterprise, then ESG can represent the long-term credit quality of the enterprise. Behind Ruixing’s financial fraud is the lack of ESG performance, which implies the moral responsibility of enterprises. In the case of frequent financial information distortion and financial report fraud, ESG information, as the key motivation information hidden behind the financial performance of enterprises, can make up for the lack of financial indicators and provide investors with evaluation methods and indicators to further understand the overall situation of the company.


  From the specific indicators, environmental indicators can evaluate the green development, environmental compliance and green degree of the whole life cycle of enterprises, which can comprehensively measure the environmental risk and green sustainable development ability of enterprises; Social indicators evaluate the performance of enterprises in public welfare activities and stakeholder protection, measure the degree of responsibility of enterprises from the perspective of stakeholders, and show the operational ability of enterprises from the side; Governance indicators evaluate the organizational structure, investor relations, information transparency, risk management, etc., and carefully consider the corporate governance capacity and long-term sustainable development capacity.


  Fourth, the reference and enlightenment significance of Ruixing incident


  (1) Regulatory body: Establish and improve the ESG information disclosure and verification system of enterprises.


  Basically, in this Ruixun incident, the regulatory authorities need to speed up the construction of ESG information disclosure system, and gradually establish and improve the corresponding auditing system and supporting mechanism. By requiring and guiding enterprises to disclose ESG information, we can help enterprises improve their credit quality and improve the overall quality of Chinese enterprises. At present, there is still a certain gap between the A-share market and the US stock market in the development of ESG information disclosure, and ESG information disclosure has not been completely enforced, which lacks standardization for the performance of listed companies in non-financial indicators. At the same time, although China’s regulatory authorities have increased the regulatory penalties for listed companies in terms of environment and governance in recent years, overall, the cost of violating laws and regulations of enterprises is still lower than that of the US stock market, and the strong binding nature of enterprises’ supervision needs to be further improved.


  In addition, the regulatory authorities should gradually reduce the regulatory barriers in domestic and foreign markets, strengthen the control and supervision of the quality of China Stock Exchange, and strengthen domestic penalties for overseas violations. The new Securities Law, which came into effect on March 1 this year, clearly states that securities issuance and trading activities outside People’s Republic of China (PRC) disrupt the market order in People’s Republic of China (PRC) and damage the legitimate rights and interests of domestic investors, and shall be dealt with and investigated for legal responsibility in accordance with the relevant provisions of this Law. Regarding the Ruixun incident, the statement of China Securities Regulatory Commission on April 3 also stated that the China Securities Regulatory Commission will check the relevant situation in accordance with the relevant arrangements of international securities regulatory cooperation, resolutely crack down on securities fraud and effectively protect the rights and interests of investors.


  (2) Enterprise: issue an ESG consulting rating report reviewed by a third party.


  From the perspective of enterprises, on the one hand, enterprises need to raise awareness of ESG information disclosure and strengthen their own ESG capacity building. Behind the events such as Ruixing in China Stock Exchange, Kangmei and Kangdexin in A-share, the ESG problem of enterprises has been exposed. Only by solving the bad habits of enterprises from the root and improving their credit quality can we avoid the recurrence of such events. On the other hand, enterprises should issue ESG consulting rating reports reviewed by third parties to enhance the credibility of ESG information disclosure data. Enterprises have the motivation to disclose information that is beneficial to them and avoid information that is unfavorable to them, so it is particularly important to issue a credible third-party review of both financial information and ESG information. At the same time, third-party review is also the second constraint on enterprises besides supervision, which can standardize enterprise behavior to a certain extent and enhance the compliance of enterprise information disclosure.


  (C) investors: pay attention to the quality and sustainability of enterprises and avoid speculative business models.


  Investors should also pay more attention to long-term value investment. The strategic mode of short-term investment is short-term and unsustainable. In order to obtain long-term sustainable returns, investors should pay more attention to the internal quality of enterprises and tap the endogenous value of enterprises. By incorporating ESG into the investment strategy, we can not only avoid environmental risks, moral risks and governance risks of enterprises, but also screen out investment targets with strong anti-risk ability and strong self-management ability when systemic risks occur, so as to alleviate the market impact and obtain higher returns. In addition, if more and more investors incorporate ESG information into their investment decisions, they can also close down enterprises to improve ESG performance, thus promoting the high-quality development of the whole market.


  Author:


  Shi Yichen, deputy dean of the International Institute of Green Finance of Central University of Finance and Economics, and dean of the Yangtze River Delta Green Value Investment Institute.


  Yang Chenhui is a researcher at the International Institute of Green Finance of Central University of Finance and Economics, and a researcher at the Yangtze River Delta Green Value Investment Institute.


  Bao Jie is a researcher at the International Institute of Green Finance of Central University of Finance and Economics, and a researcher at the Yangtze River Delta Green Value Investment Institute.


  This article was first published on WeChat WeChat official account: International Research Institute of Green Finance of Central University of Finance and Economics. The content of the article belongs to the author’s personal opinion and does not represent Hexun.com’s position. Investors should operate accordingly, at their own risk.

(Editor: Ma Yan)
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China People’s Insurance Company notified the inspection and rectification, and 156 rectification tasks were basically completed.

  People’s Daily Online, Beijing, April 25 (Xinhua) The website of the Supervision Department of the Central Commission for Discipline Inspection today released the Circular of the CPC China PICC Group Committee on Inspection and Rectification. The circular pointed out that in the past two months, the Party Committee of China PICC Group, in the spirit of nailing nails, made every effort to implement various rectification measures item by item against the feedback from the central inspection, and achieved obvious phased results. Up to now, 156 rectification tasks have been basically completed, 195 new rules and regulations have been revised, and 128 people have been held accountable.

  The following is the original text of the notification:

  According to the unified deployment of the central government, from October 30 to December 29, 2015, the 11th Inspection Team of the Central Government conducted a special inspection on China People’s Insurance Group Co., Ltd. (hereinafter referred to as PICC China). On February 1st, 2016, the 11th Inspection Team of the Central Committee gave feedback to the Party Committee of PICC China. According to the relevant provisions of the "Regulations on Patrol Work in the Communist Party of China (CPC)", the patrol rectification situation is now announced.

  First, unify our thinking, strictly follow the facts, and take patrol rectification as a major political task.

  The Party Committee of the Group regards inspection and rectification as an important opportunity to promote the party building and reform and development of the whole group, deeply reflect on problems, condense consensus on rectification, refine rectification measures, strengthen organizational leadership, and solidly promote inspection and rectification work.

  (A) unite ideological consensus and strengthen organizational leadership.

  On February 2, the Group held an enlarged meeting of the Party Committee to thoroughly study and understand the spirit of the important speech delivered by the Supreme Leader General Secretary when he listened to the report on the third round of special inspections in 2015 on January 28, and carefully studied the feedback from the inspections. Everyone agreed that the special inspections conducted by the 11th Inspection Team of the Central Committee on PICC China were accurate, insightful and thorough, which was a comprehensive physical examination of the Party Committee’s management of the party. Through study and discussion, the comrades of the Party Committee formed a "three-point consensus": First, as a strict political patrol, the problems pointed out by the Central Leading Group for Inspection Work are, in the final analysis, that the Party Committee of the Group does not have a deep understanding of the comprehensive and strict management of the Party, and that it is lax in managing the Party, taking the main responsibility and fulfilling the "one post and two responsibilities" is not in place. The rectification work must work hard to give play to the leading core role of the Party Committee of the Group. Second, China PICC Group is a financial enterprise under the central management. It should have high standards and strict requirements in comprehensively and strictly administering the Party, have a sense of "keeping pace", focus on strengthening political awareness, overall awareness and sense of responsibility, and unconditionally rectify the problems pointed out by the inspection without emphasizing objectivity. Third, the key to strictly administering the party in an all-round way is to be strict, and the core is to be governed. The rectification work should dare to expose shortcomings and expose ugliness, dare to dig deep and examine them carefully, and dare to be real and hard. Starting with the rectification of the problems pointed out by the patrol, we will push forward the rectification work of the "2016 Comprehensive Rectification Year", give full play to the positive energy of the patrol work, and promote reform and innovation through patrol rectification.Promote the sustainable and healthy development of the Group.

  The Party Committee of the Group decided to take the inspection and rectification work as a concentrated practice to fulfill "one post and two responsibilities". The Party Committee is the leading organization for inspection and rectification work, and each Party Committee member is mainly responsible for the rectification work in the field in charge. A patrol and rectification coordination group was set up, with Party Secretary Wu Yan as the team leader and Discipline Inspection Commission Secretary Zhuang Chaoying as the deputy team leader, and all subsidiaries also set up corresponding institutions as required. Comrade Wu Yan, secretary of the Party Committee, took the lead in setting an example. He interviewed 45 members of the Party Committee, the head of the headquarters department and the members of the subsidiary party Committee, and talked about how to implement "one post and two responsibilities", enhance party constitution’s awareness, and do a good job in inspection and rectification. Members of the Party Committee earnestly performed "one post and two responsibilities", took their seats accordingly, and held several special meetings of the departments in charge to specifically study the rectification work in the areas in charge. During the inspection and inspection and rectification, the Group held three special democratic life meetings of Party committees, 13 party committees, 10 disciplinary committees and 6 inspection and rectification coordination promotion meetings to study and deploy inspection and rectification work and ensure the orderly progress of inspection and rectification.

  (B) adhere to the problem-oriented and strict process control.

  The Party Committee of the Group detailed and decomposed 30 rectification tasks of the Group headquarters and 126 rectification tasks of eight subsidiaries one by one according to the feedback, forming a "three lists" of problems, tasks and responsibilities. On February 4th, the Party Committee of the Group issued the "Rectification Plan for Feedback from the Party Committee of China People’s Insurance Group on Special Inspection by the 11th Inspection Team of the Central Committee". The Commission for Discipline Inspection of the Group divided and deployed 208 letters and visits handed over by the Central Leading Group for Inspection Work to subsidiaries according to the management authority of cadres, and led by three Party committee members to form three verification teams, which went to the headquarters of relevant subsidiaries to carry out verification work. On March 11th, the Party Committee of the Group issued the Notice on Doing a Good Job in Inspection and Rectification Work again, demanding to thoroughly understand the spirit of inspection feedback and further strengthen the accountability and correction of inspection and rectification work. The patrol rectification coordination group holds regular meetings every week to coordinate and promote various rectification work. The Commission for Discipline Inspection of the Group keeps a close eye on every specific issue and goes all out to do a good job in taking the lead, supervising and coordinating, and checking and handling cases. The Office of the Coordination Group for Inspection and Rectification will follow up and implement the specific problems item by item, compile six issues of Special Inspection and Rectification work briefing, and issue it to the whole system to supervise and guide the inspection and rectification work. For some common problems in the disposal of over-standard vehicles and the verification of letters and visits, the Group defined the standards in a unified way, defined the disposal methods, and put them into practice from the headquarters to the branches, thus ensuring the unified and standardized rectification measures of the whole system and promoting the solid and strict inspection and rectification.

  (3) Pay attention to the analogy and promote both the symptoms and the root causes.

  The patrol rectification work is not only in the right place, but also pays attention to the rectification of problems pointed out by feedback; We also pay attention to digging deep into the root causes and rectifying the crux of the problem. Efforts have been made to grasp the "five combinations": First, the headquarters rectification is combined with the overall promotion of the system. The focus of rectification is on the headquarters of the Group and its subsidiaries, and some specific problems also involve the branches of the system. The Party Committee of the Group has made unified arrangements for the rectification work, linked up and down, and treated both the symptoms and the root causes, forming an overall effect. The second is the combination of highlighting key points and comprehensive rectification. The Party Committee of the Group has designated 2016 as the "year of comprehensive rectification", and comprehensively rectified the problems found by the central inspection, national audit and the "four winds" rectification deployed by the Central Commission for Discipline Inspection. The patrol rectification has established 6 key sectors and 3 key areas. For six key sectors, such as party building and organization personnel, discipline inspection and supervision, "three majors and one big", investment decision-making, agricultural insurance, and "four winds", the work plan was refined respectively to promote systematic rectification; In view of the inspection, it was pointed out that the specific problems involved three key subsidiaries, and supervision and guidance were strengthened. At the same time, the patrol rectification was combined with the audit rectification and the rectification of the "four winds" problem, and a joint coordination meeting was held to make unified arrangements and supervise the rectification. All the 128 rectification tasks pointed out by the national audit were completed, and the "four winds" problem was rectified.Looking back "to complete the self-examination. Drive comprehensive rectification with patrol rectification, and consolidate the results of patrol rectification with comprehensive rectification. The third is to adhere to the combination of correcting specific problems and establishing rules and regulations. While doing a good job in the implementation of 156 inspection and rectification tasks, the Group and the party committees of its subsidiaries formulated 195 revised rules and regulations around party building, "three majors and one big one", selection and employment, and accountability. Fourth, adhere to the combination of case warning education and typical positive propaganda. The Group has successively forwarded three batches of 38 typical cases issued by the Central Commission for Discipline Inspection, made the first batch of centralized notification on 24 typical cases investigated and dealt with by this system that violated the spirit of the eight central regulations and organizational discipline, and made the second batch of centralized notification on 8 typical cases investigated and dealt with recently. At the same time, pay attention to the leading role of positive models, and set up two models: the Party Committee of PICC P&C Zhejiang Branch strengthens the main responsibility and the Disciplinary Committee of Hunan Branch strengthens the supervision responsibility, which provides a benchmark for the implementation and rectification of the "two responsibility" in the whole system. Fifth, adhere to the combination of surface rectification and extension and deepening. In accordance with the principle that everything is settled and everything is echoed, while completing the "specified tasks" of patrol rectification, we should pay attention to forcing reform through rectification, intensify the integration construction of the Group, promote product, service and management innovation, and promote the extension and deepening of patrol rectification.

  Second, focus on the problem, treat both the symptoms and the root causes, and do our best to rectify the feedback from the central inspection.

  In the past two months, in the spirit of nailing, the Party Committee of China PICC Group has made every effort to implement various rectification measures by comparing the feedback from the central inspection item by item, and achieved obvious phased results. Up to now, 156 rectification tasks have been basically completed, 195 new rules and regulations have been revised, and 128 people have been held accountable.

  (a) on strengthening the core role of the Party Committee, the implementation of the main responsibility of the rectification.

  The Party Committee of PICC Group insists on the rectification work, first of all, we must grasp the core essence of managing the party and the party, shoulder the "hard task" of managing the party and the party, and strive to strengthen the core role of the party Committee’s leadership.

  1. Strictly implement the main responsibility. In view of the problem that the core role of party Committee leadership is not fully played, the party Committee of the group strengthens the implementation of "one post and two responsibilities", compacts the responsibilities at different levels, and strictly pursues the responsibility for the ineffective party building work. First, the party Committee team itself improves its ideological understanding. The Party Committee of the Group focused on the requirements of the central government’s political inspection, made every effort to do a good job in rectification, and the members of the team took their seats to inspect the rectification issues, and held three special democratic life meetings to carry out criticism and self-criticism. The members of the Party Committee insist on putting themselves in, putting their work responsibilities in, and taking the initiative to take responsibility. Second, for the first time, the party Committee of the subsidiary was seriously accountable. On March 24th, the Party Committee of the Group held an enlarged meeting to listen to the review of the party committees of subsidiaries with more problems in the patrol feedback. Three insurance subsidiaries, PICC P&C Insurance, PICC Health Insurance and PICC Life Insurance, deeply reflected on the outstanding problems pointed out by the patrol feedback, such as lax compliance with political discipline, lack of "three majors and one big" system, weakening of grass-roots party organizations, and irregular decision-making procedures for major investments, and made an analysis and inspection. The Party Committee of the Group approved the whole system, educating and alerting party organizations at all levels and leading cadres in party member to truly shoulder the responsibility of managing the party and the party. The third is to carry out the review of party building. The Group has formulated the "Implementation Measures for the Evaluation and Assessment of Party Committee Secretaries of Group Companies Grasping Grassroots Party Building Work", which links the assessment results with the comprehensive assessment and evaluation of party committees and party secretaries, and emphasizes the responsibility of "the first responsible person".Every year, the members of the Party Committee team should report to the Party Committee at the corresponding level on the work of grasping business and party building, and bask in the report card of "one post and two responsibilities". The Party Committee of the Group organized a debriefing evaluation on the work of Party secretaries of eight subsidiaries and executive deputy secretaries of government party committees at the grass-roots level, and listened to the debriefing of party construction of subsidiaries. The Party Committee of the Group organized a debriefing evaluation on the work of the secretary of the Party branch (general party branch) of the headquarters department of the Group. The evaluation results were included in the year-end performance appraisal. The fourth is to sign the responsibility certificate step by step. In accordance with the spirit of the Group’s Guiding Opinions on Implementing the Main Responsibility of Building a Clean and Honest Party Style, the content of the responsibility of strictly administering the Party was enriched and improved. The Party Committee Secretary of the Group and the Party Committee Secretaries of eight subsidiaries signed the Responsibility Certificate for Strictly Administering the Party in an All-round Way, which was systematically decomposed layer by layer, and a total of 5,014 main responsibility certificates were signed. The implementation of "two responsibility" will be included in the Group’s key work in 2016, and the party building work will be included in the 2016 key performance indicators assessment system for the principal responsible persons of subsidiaries.

  2. Improve grassroots party organizations. The Party Committee of the Group has made great efforts to solve the problem that the Party’s leadership lacks organizational support at the grassroots level, and strived to lay a solid foundation for Party building at the grassroots level. First, complete and improve the party committees of provincial branches. In view of the imperfection of some provincial-level institutions of PICC Life Insurance and PICC Health Insurance, in 2015, the Group selected 25 PICC P&C cadres to exchange with PICC Life Insurance and PICC Health Insurance. Nine provincial-level institutions with fewer members of PICC Life Insurance have all been equipped in place; People’s Insurance Company of China (PICC) still lacks a member of the Party Committee in Guangdong and Dalian branches, and is currently in communication and planning to exchange candidates. The second is to promote the full coverage of party organizations at the grassroots level. In view of the large number of branches in districts and counties and the imperfect party organizations, the Interim Provisions on the Construction of Joint Party Branches have been formulated to strengthen the effective coverage of party organizations in four-level institutions through the establishment of joint party branches. At present, the whole system should set up 1490 joint party branches, of which 1432 have been set up and 58 are being set up, and the coverage rate of established joint party branches reaches 96.11%. Organize the development and application of the "Party Building Cloud" platform to build an online community for party member, party workers, grassroots party branches and grassroots party committees to work, learn and communicate. Third, precisely regulate the development of grassroots party member. The Group issued the Notice on Regulating party member’s Development Structure and Perfecting Grassroots Party Organizations, requiring branches at all levels to implement targeted regulation and control on party member’s development, and increase efforts to develop party member in key positions.In 2016 and 2017, we will focus on the development of party member in municipal, district and county institutions, so as to realize the wide coverage of district and county institutions by Party organizations. The fourth is to formulate plans for the construction of grass-roots party organizations. The Group has formulated the "China People’s Insurance Group’s 2016-2018 Plan for Strictly Strengthening the Construction of Grass-roots Party Organizations", which systematically solves the outstanding problems in the construction of grass-roots party organizations from the aspects of improving ideological understanding, improving organizational support, strengthening system construction, strengthening the implementation of responsibilities, and strict assessment and supervision. It is clear that in 2018, the establishment of party committees in prefecture-level institutions will reach 100%, and the establishment of party branches in district and county institutions will reach more than 50%; It is required that 175 prefecture-level institutions with imperfect party committees of PICC Life Insurance should be fully equipped before the end of September 2016, and provincial, prefecture-level branches should study and formulate the working rules of party organizations at the corresponding level before the end of June 2016.

  3. Fully implement the "three majors and one big" decision-making system. The Party Committee of the Group strictly implements the system of "three majors and one big" in the whole system, and strengthens political discipline and rules. The first is to seriously rectify outstanding problems. In view of the problem that PICC P&C Subsidiary failed to issue and implement the Group’s implementation measures on the "three majors and one big" decision-making system in time, the Party Committee of PICC P&C Subsidiary was instructed to reflect deeply. The Party Committee of the company made a review and serious rectification, revised the Decision-making Measures of the Party Committee for Further Implementing the System of "Three Heavies and One Big", the Amount Standard of the Decision-making Items of the Party Committee and the Explanation of the Core Elements of the Meeting of the Party Committee, and further refined the scope standards, decision-making procedures, implementation requirements and supervision and accountability of the "Three Heavies and One Big". Revised the Manual of Power and Responsibility Norms (2016 edition) to further improve the relationship between collective decision-making and authorization management. In view of the problem that the top leaders of some provincial branches are not strict and standardized in complying with the relevant systems of "three majors and one big", the relevant subsidiaries are required to rectify within a time limit. PICC Life Insurance Company has revised the Implementation Measures for the "Triple and Big" Decision of the Party Committee of the Head Office and the Party Committee of the Provincial Branch.The "Measures for the Implementation of the" Three Heavy and One Big "Decision-making" has trained the party committee secretaries at provincial and prefecture levels in the "three heavy and one big" decision-making system and the scope of discussion, added the "three heavy and one big" decision-making information filing module of provincial branches in the OA system, and uploaded the meeting minutes of party committees as the daily management and off-site supervision platform of the head office to promote the standardized operation of the "three heavy and one big" decision-making matters of branches. The second is to continue to rectify universal problems. Before the inspection, the Party Committee of the Group organized all subsidiaries to conduct a comprehensive self-inspection of the implementation of the "three majors and one big" decision-making system. Members of the Party Committee of the Group led eight working groups to conduct spot checks on 22 provincial branches, and found 130 problems in the implementation of the "three majors and one big" decision-making system, put forward 51 rectification opinions, and the provincial branches formulated 206 rectification measures. During the inspection and rectification, focusing on the common problems found in self-inspection and spot checks, the Group continued to follow up and supervise the implementation of rectification in three aspects: system construction, implementation of basic procedures, supervision and accountability, and severely dealt with and notified those who violated discipline.

  4. Make overall plans to promote party building. The Party Committee of the Group firmly established the concept of "doing a good job in Party building is the greatest achievement" and enhanced the consciousness of implementing the main responsibility of strictly administering the Party in an all-round way. First, clearly and regularly study the party building work system. The Party Committee clearly holds a special meeting of the Party Committee at least once a month to study the party building work, and requires the party committees of all subsidiaries to establish a system of special research on the party building work. Party committee secretaries at all levels teach party classes at least once a year. The second is to comprehensively coordinate the party building work. Incorporate the party building work into the Outline of the Group’s "Thirteenth Five-Year Development Plan", and comprehensively coordinate the party building work from four aspects: strengthening the implementation of "one post and two responsibilities", improving the organizational system, institutional system and supervision and evaluation system of party building work. The third is to carry out the education of strictly administering the party. Grasp the learning system of the Central Committee of the Party Committee, formulate and implement the "Learning Plan for the Central Committee of the Party Committee of the Group in 2016", and deploy and study the spirit of the previous central meetings since the 18 th National Congress of the Communist Party of China and the spirit of the series of speeches by the General Secretary of the Supreme Leader. Grasping the backbone education, 460 people, including the group headquarters, members of the party committees of subsidiaries, and discipline inspection cadres of provincial branches, have been organized to conduct centralized training on party building and discipline inspection and supervision in enterprises. Grasp the education in party member, plan and promote the "two studies and one work" study and education, and promote the comprehensive and strict management of the party to the grassroots. Grasping the discipline education of employees, the Commission for Discipline Inspection of the Group has formulated the "Red Line Manual for Integrity", which defines the "red line" in nine aspects.On this basis, guide all subsidiaries to formulate the company’s "red line manual", form a "1+N" series of teaching materials, and carry out discipline education for all employees.

  (two) strict rules and procedures, standardize the rectification of the organization and personnel work.

  On February 23, 2016, the Party Committee of the Group organized a meeting on personnel rectification of the Group, focusing on the whole process of selecting and employing people.

  1 resolutely investigate and deal with illegal employment problems, and seriously organize personnel work discipline. Comprehensive verification, resolutely correct and correct, and seriously investigate the responsibility of relevant personnel. Dismissal and re-arrangement of two relatives of the head of the branch who were promoted in violation of regulations; The labor contract was terminated for one relative transferred in violation of regulations, and one person was reassigned; Of the 19 cadres who were promoted in violation of regulations, one who did not meet the requirements has been dismissed, and the remaining 18 have been evaluated democratically, and will put forward treatment opinions in combination with performance appraisal; Serious accountability was given to those responsible for the appointment and dismissal of cadres by online office countersignature without the study of the party Committee; Of the two cadres who were "promoted with illness", one was given a serious warning and administrative dismissal within the party, and the other was cancelled; Administrative dismissal of one person whose original treatment was not in place. Those responsible for employing people in violation of regulations were investigated for responsibility, and 4 people were given disciplinary sanctions by the party and government.

  2. Standardize the procedures for selecting and employing people and broaden the channels for selecting and employing people. From the first step of selecting and employing people, the Group formulated and promulgated the Detailed Rules for the Brewing of the Proposal for Selecting and Appointing Cadres to standardize the brewing process of the proposal for selecting and appointing cadres and the recommendation motion behavior of leading cadres, especially the "top leaders"; Broaden the horizons of selecting and employing people, formulate and implement the "Implementation Measures for Competitive Posts for Managers in Group Headquarters", and pay attention to selecting and transferring cadres from the grassroots level; The Interim Measures for Employees’ Post Training was issued, and the two-way exchange between the headquarters and subsidiaries of the Group was continued. By improving the openness and transparency of the selection and employment of personnel at the headquarters, the guiding role under the above rate was brought into play.

  3. Strengthen the management of the selection and employment process, and put an end to the phenomenon of "illegal promotion or even promotion of cadres despite illness". Issued the "Detailed Rules for the Implementation of the Request for Filing of the Selection and Appointment of Leaders of Subsidiaries", which made more detailed audit requirements for leapfrog promotion and exceptional promotion; The "Documentary Essentials of Cadre Selection and Appointment" was formulated, and the qualification conditions, nomination brewing, recommendation, inspection, research decision, publicity, appointment and dismissal of cadres were recorded in the whole process; The detailed rules for the implementation of pre-appointment talks for newly promoted cadres were issued by the group headquarters to strengthen the propaganda of cadre education and supervision policies.

  4. Improve the cadre supervision system and strengthen the supervision of selecting and employing people. The headquarters of the Group has set up a separate cadre supervision office, each subsidiary has set up a cadre supervision office separately or jointly, and the provincial organizations and personnel departments of the three major insurance subsidiaries have set up cadre supervision posts. Deepen the implementation of the Group’s Guiding Opinions on Strengthening the Supervision of Cadres, and urge major subsidiaries to formulate the Implementation Measures for the Supervision of the Selection and Appointment of Cadres. The "Ten Must-Check Notice" was issued to clarify the necessary checks and checks in the selection and appointment procedures of cadres, so as to prevent "promotion with illness" and "taking up posts with illness". The Special Inspection Measures for the Selection and Employment of Subsidiaries and the Detailed Rules for the Implementation of "One Report and Two Comments" for the Selection and Employment of Subsidiaries were issued to strengthen the penetrating inspection of the selection and employment of institutions at all levels of the system and strengthen the supervision of the selection and employment.

  5. Strictly implement the reporting system for personal matters, in order to solve the problem of "‘ Everything must be nuclear ’ The implementation is not strict. The Group issued the Notice on Doing a Good Job in Reporting Personal Matters by Leading Cadres in 2016, clarifying that the scope of reporting personal matters is extended to the heads of the headquarters departments of the Group and subsidiaries, the heads of the headquarters departments of provincial institutions, and the personnel above the members of the municipal institutions; Complete the configuration of the report system software and the input and summary equipment of the institutions above the provincial level; Formulated the "Detailed Rules for the Implementation of the Group’s" All Mention Must Be Checked "to standardize the whole system’s" All Mention Must Be Checked "work. During the inspection, two leading cadres of branches who failed to report personal matters as required were dismissed and dismissed respectively, and were notified on the website of the Supervision Department of the Central Commission for Discipline Inspection. For the problem that the heads of the headquarters departments of provincial institutions and the members of the municipal institutions failed to "check everything before promotion", the relevant subsidiaries were instructed to carry out supplementary verification of personal matters. In March, the supplementary verification information of personal matters of all 1,552 people was reported to the Cadre Supervision Bureau of the Central Organization Department.

  6. Implement the work of "defining departmental responsibilities, internal organs and staffing" and solve the problem of "overstaffed cadres". Before the end of June, 2016, formulate the Human Resources Plan for the Group Headquarters, revise the Measures for the Management of Sequential Personnel and the Measures for the Management of Professional Sequential Personnel, and clarify the positions of heads of departments and offices at the headquarters. At present, 24 of the 47 cadres who have been checked out by themselves have been digested, and 14 departmental management posts of 7 provincial-level institutions and 9 team members of 4 prefecture-level institutions have not been adjusted. In March 2016, PICC P&C issued a "military order" that was digested before the end of the year. The Notice on Strictly Managing the Positions of Leaders in Subsidiaries was issued, urging subsidiaries to carry out the "three-fixed" work, and requiring subsidiaries with company-level executives to issue the "Regulations on the Management of Senior Management Positions" before the end of April 2016, so as to plug the loopholes in arbitrarily setting job names and company-level executives from the source.

  7. Carry out special work to solve the problem of "rampant nepotism". The headquarters of the Group has been expanded everywhere to find out the position of relatives of leading cadres in the system. According to the unified deployment of the Group, PICC P&C has carried out the second round of thorough investigation, and investigated 233 cases that need to be avoided, and rectified the cases that should be avoided within a time limit; PICC Life Insurance has completely rectified 52 people who violated the avoidance of relatives; Other subsidiaries have also earnestly implemented the rectification requirements. Taking the headquarters of the Group as a pilot, we will establish a commitment mechanism for avoiding employment in recruitment, verify the employment status of close relatives in the system in the process of comprehensively promoting recruitment in the Group, and refuse to hire those who should be avoided, so as to prevent nepotism from the source.

  8. Improve the system and mechanism, and plug the management loopholes of "lax implementation of retirement policies", "spamming subsidies", "going abroad illegally for private reasons (territory) and going abroad without approval". The regulations on the dismissal and retirement of people who have reached the age have been strictly defined, and the rectification plan for the problem that the members of the PICC P&C insurance team have not retired has been formulated and is being implemented. The Notice on Strengthening the Management of Total Wages was issued, which standardized the channels for paying salaries and strictly implemented the provisions on deferred payment of salaries. Improve the Interim Measures for Welfare Management of Group Companies and strengthen the welfare management of the group. Revised the Group’s Interim Measures for the Administration of Going Abroad for Private Purposes, and further tightened the management of certificates for going abroad, examination and approval authority and procedures, and accountability. The verification mechanism for accepting and reporting cases of letters and visits by selecting and employing people was further improved, and 8 cases were verified in March, exceeding the number in previous years.

  (3) Rectification of strict rules and regulations and strengthening supervision and accountability.

  The Party Committee of the Group fully supports the work of the Commission for Discipline Inspection, improves the organizational system of discipline inspection and supervision, strictly and promptly investigates and deals with violations of discipline according to discipline, and resolutely stands up discipline and rules.

  1. Focus on disciplinary review to form a deterrent. The Party Committee of the Group attaches great importance to the problem clues assigned by the Central Leading Group for Inspection Work and letters and visits from the masses. The Secretary of the Party Committee personally supervises, and the Secretary of the Discipline Inspection Commission directs, uniformly deploys personnel, and concentrates on disciplinary review, strengthening discipline and establishing rules. During the inspection, the Group seriously investigated and dealt with 32 clues, of which 24 were assigned by the Central Inspection Team and 8 were self-inspected. It also dealt with 75 people who violated the rules and went abroad for private reasons. A total of 133 person-times were investigated for responsibility, of which 23 were punished by Party discipline, 10 by political discipline and 100 by organization. The broad masses of cadres and employees of the group responded strongly and played a deterrent role. During the rectification period, the accountability for discipline has not diminished, and the scale is not loose. We will continue to be strict and realistic, and consolidate the results of inspection and rectification. A total of 2 batches of 208 letters and visits handed over by the Central Inspection Team were verified. Among them, the Commission for Discipline Inspection of the Group organized 14 letters and visits by itself, and the rotor company handled 194 letters and visits. At present, the initial verification of all the letters and visits has been completed. In view of the verified problems, there are 128 persons who violate the rules and regulations (34 disciplinary actions, 34 disciplinary actions, and 60 organizational handling and criticism and education), involving 26 group management cadres or employees of the group headquarters. Among them, there are 14 clues about mental problems that violate the eight central regulations, and 30 people who violate the rules and regulations have been dealt with and entered the processing procedure (17 disciplinary actions, 2 disciplinary actions, and 11 organizational handling and criticism and education);There are 3 clues about violations of political discipline that have been verified, and 3 people who have been dealt with and entered the handling procedures (1 person was disciplined by the party and 2 people were organized to deal with it).

  2. Deepen the rectification of the four winds issue. First, seriously carry out the "four winds" rectification and "look back". We comprehensively sorted out the "four winds" problem and its rectification found by the feedback from the central inspection, the party’s mass line education practice activities, the "three strictness and three realities" special education activities, the feedback from the Commission for Discipline Inspection to the party committees at the same level, and the clues of letters and visits, and formed a list of rectification problems step by step, so that all the items were settled. The "four winds" problem fed back by the Central Leading Group for Inspection Work has been decomposed and implemented 161 times in the system (including the data of rectification and implementation of the same problem in different subsidiaries and institutions at different levels, the same below), and 136 times have been rectified; 6,193 other "four winds" problems found and rectified, 5,182 have been rectified, 1,010 are being rectified, and 1 listed plan has not been rectified; The Central Leading Group for Inspection Work assigned 62 clues to the "four winds" problem, 61 of which have been completed and 1 is being rectified; 112 other clues involving the "four winds" issue have been completed; The Group and its subsidiaries took the lead in carrying out 13 special rectification activities on "four winds". The second is to standardize salary and benefits. Regarding the problem of illegal and over-standard payment of salaries and expenses under various pretexts,Instruct the parties to return the payment, and thus strictly enforce the rigid provisions and disciplinary requirements of salary and welfare. In strict accordance with the Ministry of Finance’s "Administrative Measures for the Audit of the Remuneration of Heads of Central Financial Enterprises", we will fully recover the salaries that three leading cadres have received in violation of regulations. According to the requirements of the Group, all subsidiaries shall comprehensively clean up the subsidized projects in Tianjin, and stop issuing benefits such as meal allowance, communication fee and holiday fee; Completely stop insuring for "small groups" at ultra-low rates, and the premium rate in the later period is in line with the market price level, and the previous premium has been paid back, and personal income tax has been paid back gradually; Strictly dispose of vehicles that exceed the standard. After the release of the eight central regulations, the whole system purchased 73 official vehicles that exceed the standard. Through the evaluation of professional institutions, 56 vehicles have been publicly auctioned, and other vehicles are being processed; Further improve the business management system, improve the management regulations of brokerage agency business, standardize the avoidance of relatives of leading cadres in business operations, and resolutely put an end to nepotism and related transactions. The third is the outstanding problem of special rectification. Comprehensively self-examine the problem of going abroad (abroad) illegally, and ask 75 leading cadres involved to make a review at the democratic life meeting and informed criticism. Two people were dismissed from their posts in the Party, three were given warnings in the Party, two were given administrative warnings, one was removed from his post and restricted from leaving the country for one year, four were restricted from leaving the country for one year, 24 were admonished, two were given warnings in the Party and one was removed from his post. Revise and improve the Interim Measures for the Administration of Group Going Abroad for Private Purposes, and will go abroad.The centralized management of certificates has been expanded from department level to all levels, and the approval module for going abroad for personal reasons has been added to the office system to standardize the approval process. The whole system has centralized management of 3058 certificates for going abroad for personal reasons.

  3. Strong governance of illegal business problems. In view of the illegal business problems such as false intermediary, false expenses, false underwriting of agricultural insurance and claims settlement, we will increase accountability. The first is to comprehensively start the rectification of agricultural insurance problems. For 67 judicial cases of agricultural insurance that occurred since 2013, we will strengthen the accountability and correction of relevant responsible personnel. Of the 76 people involved in the case who have been concluded by the judicial organs, 59 have been held accountable, including 19 disciplinary actions, 37 disciplinary actions and 22 organizational actions. For the false claim of planting insurance of a company in Henan Province in 2013, the relevant personnel were investigated step by step, and a total of 13 people were held accountable. On February 26th, 2016, the Group held the 10th system-wide rural insurance work conference to implement the spirit of Document No.1 of the Central Committee, requiring the whole system to treat the rural insurance from the perspective of serving the transformation of government functions, innovating social governance and people’s livelihood, and to continuously expand the rural insurance with new measures such as improving management and control mode, strengthening platform construction and improving service and support capabilities. PICC P&C was instructed to formulate the Inspection and Rectification Plan of the Agricultural Insurance Division, and issued the Notice on Implementing the Feedback from the Central Inspection to Carry out Agricultural Insurance Rectification in an All-round Way, so as to carry out agricultural insurance rectification in a comprehensive, systematic and in-depth manner, implement the whole process business management of agricultural insurance, realize the close interaction and risk balance between agricultural insurance underwriting and claims, and effectively control the behavior of false underwriting and claims. Second, in-depth rectification in the fields of intermediary management and expense management. Up to now, the amount of false intermediaries has been rectified by measures such as account adjustment and fund recovery, totaling 140 million yuan;Through measures such as increasing the taxable income of enterprise income tax, recovering funds, and paying back personal income tax, the amount of fictitious expenses has been rectified by 480 million yuan. And further improve the long-term rectification measures: in strengthening expense management, formulate a standardized financial system for expenses, optimize various expense allocation systems, and improve the salary quota allocation model; In terms of strictly controlling the withdrawal of funds through fictitious intermediary business, we should improve the internal control system of intermediary business management, seriously examine and manage the intermediary qualification access, and strictly monitor and inspect the intermediary business process. The third is to focus on strengthening the special governance of violations of laws and regulations by grassroots branches. On March 3rd, the Group held a kick-off meeting on the construction of internal control system for branches at the prefecture, county and district levels, and implemented the framework model of internal control system in all institutions at the prefecture, county and district levels of three insurance companies. Grass-roots internal control model will bring integrity risk into the control scope, and accelerate the construction of a strict and standardized operation control system for processes including people, finance and materials. By improving the control system and strengthening accountability, the problem of frequent cases in grass-roots branches can be solved.

  4. Strengthen the construction of discipline inspection and supervision organization system. Implement the regulations of party constitution, return to the responsibility of discipline inspection and supervision, effectively promote the work of "three changes" and build a discipline inspection and supervision team with iron discipline. The first is to improve the discipline inspection and supervision organization. In February, 2016, the Supervision and Audit Department of the Group was formally set up and operated independently, which increased the number of offices and establishments in the discipline inspection and supervision department. Instructed the headquarters of six major subsidiaries to set up independent supervision departments, and the setting work was basically in place. It is explicitly required that qualified provincial branches independently set up discipline inspection and supervision departments, and all provincial branches of insurance subsidiaries are equipped with full-time discipline inspection and supervision cadres. Since the inspection, the system has added 52 full-time supervisors. The second is to increase the clean-up efforts of the secretary of the Disciplinary Committee. At present, the secretary of the Disciplinary Committee of the Group, subsidiaries and provincial branches all quit from the responsibilities related to people, finance and materials, and only take charge of the functional departments related to supervision, such as discipline inspection and supervision, auditing, compliance and risk management, and focus on the main business of supervision, discipline and accountability. For provincial branches with too few team members and it is difficult to form a separation of powers when the secretary of the Disciplinary Committee withdraws from business management, the relevant subsidiaries have been instructed to formulate a work plan for the staffing of provincial institutions and adjusting the division of work of the secretary of the Disciplinary Committee to solve the problem within a time limit. The Group’s 2016 discipline inspection and supervision meeting has clearly put forward targeted measures and requirements for the problem of insufficient discipline inspection and supervision power of prefecture-level institutions. Up to now, PICC P&C Insurance, PICC Health Insurance and PICC Life Insurance have formulated specific plans for the staffing of local branches and the division of labor among disciplinary committee secretaries and submitted them to the Group Disciplinary Committee.According to the documents issued by the Party Committee and the Commission for Discipline Inspection of the Group, the whole system is establishing and improving the evaluation mechanism for the secretary of the Commission for Discipline Inspection, which is mainly based on the higher-level Commission for Discipline Inspection and the organization of personnel departments. The third is to improve the ability of supervision and discipline. The Group has issued the Manual of Integrity Education in the Whole Process of Hierarchical Classification, which distinguishes different levels and posts, and defines the key contents, methods and frequencies of integrity education. The Commission for Discipline Inspection of the Group organized and wrote five practical courseware, such as "Discipline Inspection", "Letters and Visits Check" and "Integrity Risk Prevention and Control", which were distributed to the whole system for training. Before February 21, the first batch of training for disciplinary Committee secretaries and discipline inspection and supervision backbones of institutions above the provincial level was completed. During the inspection and rectification, the Commission for Discipline Inspection of the Group established a collective research system for problem clue handling and disciplinary review, which provided a basis for the problem clue handling of the Group and its subsidiaries and further standardized the problem clue handling. The Commission for Discipline Inspection of the Group regularly organizes the departments of audit, compliance, risk management and investment, finance and business development to communicate information, and feeds back the management problems found by the discipline inspection and supervision departments to the relevant functional departments to build a collaborative supervision mechanism.

  5. Strengthen grasping early and grasping small. Revise and issue the Regulations on Inspection Work of PICC China Group, and formulate the Group’s Inspection Work Plan for 2016. On the basis of full coverage of subsidiaries’ inspections, focus on key matters and key people, and carry out special inspections for provincial branches with many problems, so as to play the role of the sword of inspections and promote the comprehensive and strict management of the party to the grassroots. The Group has formulated and promulgated the Interim Provisions on Standardizing the Handling of Reminding Conversations, Admonishing Conversations and Letters and Inquiries, which will institutionalize and normalize early grasping and small grasping. In the disciplinary review, the system of "double investigation of one case" was strengthened, focusing on "one post and two responsibilities" to carry out "double investigation of one case", highlighting accountability, and forcing leading cadres in party member to assume the main responsibility of building a clean and honest party style. People’s Insurance Company of China held a special party committee to deeply reflect on the problem of poor reporting and handling measures of Hebei and Liaoning branches, and made an in-depth analysis of this problem as a typical example of the party committee’s failure to perform its duties as the main responsibility. The party committee of People’s Insurance Company of China specially reported the inspection report to the party committee of the group. During the inspection and rectification period, a total of five people were investigated by party discipline and political discipline because their main responsibilities and supervisory responsibilities were not in place. The secretary of the Party Committee of the Group directly interviewed the secretary of the Disciplinary Committee of a subsidiary that approved the report letter to the reporter. In order to deal with one education, a major case notification system has been established. Since the central inspection, institutions at all levels of the system have carried out various warning education for 261 times, covering more than 270,000 cadres and employees.

  (four) on strengthening the awareness of reform and promoting the development of rectification.

  Focusing on the key tasks such as implementing the central decision-making and deployment, implementing the overall strategy of the Group, and integrating internal resources, the Party Committee of the Group exerts the positive energy brought by the central inspection, forcing reform and improving the management level of the Group.

  1 resolutely implement the central decision-making and deployment, and actively fulfill political, economic and social responsibilities. The Party Committee of the Group further improved its political acumen, insisted on positioning the insurance and investment business from the height of stressing politics and taking care of the overall situation, and consciously fulfilled its social responsibilities. First, implement the party’s policy of strengthening agriculture, benefiting farmers and enriching farmers. PICC P&C is required to take the reform of the Agricultural Insurance Division as the starting point, improve the business model and management model, and carry out in-depth rectification of agricultural insurance. Increase the development of aquaculture insurance business, and turn it into a profit-oriented development value-oriented one. Improve the compensation ability of agricultural insurance products, and reduce the starting point of compensation for drought and pest losses from 70% to 30% in 2015 to ensure that more farmers can get insurance compensation after the disaster. Focusing on the implementation of the State Council’s opinions on promoting health service industry and accelerating the development of modern insurance service industry, we will actively develop long-term care insurance products and cooperate in the pilot project in Haidian District, Beijing to provide long-term care guarantee for disabled people; Actively develop rural inclusive insurance products, and successively launched 18 micro-insurance products, forming a relatively complete rural micro-insurance product system; Launched the sales of insurance products for a better life in Dalian pension community, and further explored the mode of combining pension community with insurance products; In view of the national health insurance personal tax preferential policy, actively participate in the personal tax preferential health insurance pilot, develop personal tax preferential health insurance products, and take the lead in launching in the whole industry; Focusing on the scientific and technological innovation of insurance services, we will increase the development of scientific and technological insurance products and gradually establish a sound scientific and technological insurance system.The Group is formulating the Supervision System on Implementing the Central Economic Work Principles and Policies, which will implement a series of important arrangements made by the CPC Central Committee, the State Council and the industry supervision departments on insurance to support economic and social development, and will be incorporated into the Group’s business supervision system for subsidiaries, which will be supervised on a monthly basis. Second, the Party Committee of the Group strengthens the organization and leadership of medium and long-term planning. The Group set up a leading group headed by the Party Secretary and attended by other team members, initiated the preparation of the Group’s 13th Five-Year Plan, and strengthened the Party Committee’s research and decision-making on the Group’s overall, long-term and fundamental major issues. We established and implemented the annual business plan and key work arrangement system, issued the 2016 Key Work Arrangement Table, and established 109 annual key work items in 7 categories of the Group, which transformed the major strategy and deployment of the Party Committee of the Group into concrete measures. Third, the Party Committee of the Group strengthened its duties and responsibilities. Resolutely implement the central government’s decision-making and deployment, and study and introduce relevant measures around key areas of economy, society and people’s livelihood, such as serving agriculture, rural areas and farmers, catastrophe protection, social governance, and medical security: building a more professional, open and effective insurance platform for agriculture, rural areas and farmers, vigorously developing rural inclusive finance, and extending rural insurance service chain and value chain; Continue to promote the pilot project of catastrophe insurance and supplement and improve the disaster relief system; Actively develop comprehensive public security, medical liability insurance, food safety liability insurance, environmental pollution liability insurance and other types of insurance related to the national economy and people’s livelihood to better protect and improve people’s livelihood; Set up a social medical insurance center from top to bottom, and establish and improve the franchise mechanism. Adhere to the problem orientation,Study and promote the pilot project of housing reverse mortgage pension insurance. Actively explore the old-age insurance security model combining medical care with nursing care, and build a healthy old-age industrial chain model with people’s insurance characteristics.

  2. Strengthen internal control and promote the integration of the Group. The Party Committee of the Group seized the bull’s nose of strategic management and control, led the integration construction of the whole group, and made efforts to solve the problems such as "the management chain of the Group is too long, the management and control power is poor, the resource integration is not in place, and the core competitiveness is not strong". First, strengthen the organic connection between the group strategy and the subsidiary strategy. Organize all subsidiaries to formulate and improve their own strategies according to the Group’s 13th Five-Year Plan, so as to ensure that the goals of the whole group are consistent and mutually supportive, and avoid the disconnection between the upper and lower levels and the out-of-control strategy. Promote the relevant functional departments of the Group to prepare functional plans such as human resources, capital management, business development, strategic asset allocation, information construction, brand building and risk management, refine the action plan, and realize the organic combination of the overall planning and special functional planning of the Group. Prepare a three-year rolling plan and adjust the medium and long-term strategy in a timely manner. Conduct a strategic implementation evaluation once a year, and instruct all subsidiaries and relevant functional departments to submit planning implementation evaluation reports on an annual basis, and rectify problems in time to ensure that the development of each business unit is always consistent with the strategic direction of the Group. The second is to promote the resource integration of the Group with the construction of four platforms as the starting point. Firmly and steadily promote integration, focus on organizing and coordinating the "four platforms" projects of unified big data platform, unified customer sharing platform, unified e-commerce platform and unified health management platform, start the formulation of unified security policy, promote mobile internet projects, and unify incremental and integrated stocks.Comprehensively improve the level of information sharing and centralized management and control of the Group. The Management Measures for the Group’s Unified Information Security Strategy was formulated and issued. The infrastructure of the Group’s unified big data platform and the Group’s unified customer sharing platform have been basically completed. The Group’s unified e-commerce platform has achieved initial results relying on PICC P&C Insurance, and the Group’s unified health management platform has entered the construction and implementation stage relying on PICC Health. The third is to promote the construction of an integrated comprehensive risk management system with the focus on three projects. In order to meet the actual needs of the Group’s overall listing and consolidated risk management, the Group launched three projects, namely, risk preference system, economic capital model and risk basic data platform phase II, which were accepted on March 22nd. Through the gradual downward decomposition of the group’s overall risk preference (total risk), the risk budget is formed, and the risk management responsibility is implemented at all levels of the group company and subsidiaries, forming visible and tangible risk constraints, and unifying the decentralized risk management work under the two-level corporate governance structure of the group to the overall strategic objectives of the group. The completion of the three projects has unified the risk management policies of the whole group and improved the professional and technical level of risk management of the group.

  3. Strengthen business collaboration and enhance the overall competitiveness of the Group. Taking solving the cross-cutting problem of medical insurance business as the breakthrough point, we will focus on strengthening the cooperation between PICC P&C Insurance and PICC Health Business, promoting the cross-interaction among the three subsidiaries of Production, Health and Life Insurance, establishing a cooperative mechanism between the insurance sector and the investment sector, and enhancing the group’s joint efforts. First, vigorously rectify the lack of coordination in medical insurance business between PICC P&C Insurance and PICC Health. The Group has successively formulated and issued Opinions on Standardizing the Benefit Distribution Mechanism of Cross-selling, Cooperation Agreement on Jointly Carrying out Serious Illness Insurance for Urban and Rural Residents, and Notice on Further Strengthening the Cooperation of Serious Illness Insurance Business, resulting in malicious competition in informed criticism. The Plan of Health Insurance Reorganization and Integration of China People’s Insurance Group was formulated and implemented, which promoted the integration of medical insurance business through equity integration, and promoted the two subsidiaries of PICC P&C Insurance and PICC Health to deepen resource sharing and strengthen business collaboration in the fields of government-commissioned business such as medical insurance and health industry chain expansion. Formulate institutional measures to eliminate cross-business conflicts, clarify the responsibilities and rights of all parties, and reduce internal disorderly competition. The second is to strengthen the synergy mechanism between the investment sector and the insurance sector. The Group has established the Investment Committee for Strategic Asset Allocation, which serves as the investment decision support platform at the group level, with the participation of insurance companies and investment sectors, to collectively study and coordinate major issues such as major strategic investments and strategic asset allocation. The Group took the lead in establishing a regular roadshow mechanism for internal asset management products and building a communication platform between insurance companies and investment companies.Implement task decomposition and index assessment for the investment sector to drive the growth of insurance business. The investment assets of the three insurance subsidiaries in the group have all been entrusted, forming a unified investment standard. The third is to promote the development of cross-interactive business. Vigorously promote key projects such as the Group’s unified customer sharing platform, customer grouping management and in-depth analysis, and the Group’s integrated sales support platform, and constantly consolidate the foundation of customers and sales channels for cross-interaction. Focusing on the construction and improvement of key mechanisms such as "unified job number", cross-selling commission settlement and cross-selling into the basic law assessment, it has promoted the optimization of business processes and the establishment of interest mechanisms related to cross-interaction among the three subsidiaries of Production, Health and Life. Actively promote the co-construction and sharing of rural power grids and community stores, provide integrated insurance services rooted in the community, and build an efficient coordinated development mechanism. In 2015, China PICC Group realized cross-interaction premium income of 26.175 billion yuan, up 13.8% year-on-year.

  Third, take the opportunity of inspection and rectification to comprehensively deepen the strict management of the party and promote the sustained and healthy development of PICC Group.

  Two months’ comprehensive rectification has achieved phased results, but this is only a new starting point for China PICC Group to strictly manage the party in an all-round way. The Party Committee of the Group will continue to give full play to the positive energy of the special inspection by the Central Committee, thoroughly study and implement the spirit of the series of important speeches by the Supreme Leader General Secretary, further strengthen the main responsibility of managing the party and the party, and turn the positive energy inspired by the inspection and rectification work into a strong driving force for the Group’s reform and development with a more energetic spirit.

  (1) Strengthen responsibility and comprehensively promote the strict administration of the party.

  The Party Committee of the Group will further enhance its political consciousness, overall situation consciousness, core consciousness and conformity consciousness, strengthen its main responsibility, give full play to the leading core role of the Party Committee, and resolutely shoulder the "hard task" of managing the Party. Conscientiously implement the "one post and two responsibilities", deploy, implement and check the party building and the group management together, strengthen the accountability of assessment, and do a good job in the debriefing of party Committee secretaries and the evaluation of party building work, so as to truly turn the main responsibility into a "hard indicator". Improve and perfect the grass-roots party organizations, promote the standardization of grass-roots party building work, and put an end to the gradual weakening of party building work within the group. Adhere to the problem-oriented, "learning" should be guided by problem learning, and "doing" should be changed according to the problem. The study and education of "two studies and one doing" should be carried out in two levels, namely, the headquarters of groups and subsidiaries, provincial and lower branches, so as to effectively consolidate educational practice activities and the achievements of "three strictness and three realities" special education, promote the comprehensive and strict management of the party to the grassroots level, and provide a strong organizational guarantee for the integrated construction and customer-centered transformation and development of PICC Group.

  (2) Strengthen the accountability of supervision and discipline, and resolutely stand up discipline.

  Respect party constitution, strictly implement the Code of Integrity and Self-discipline in the Communist Party of China (CPC) and the Regulations on Disciplinary Actions in the Communist Party of China (CPC), effectively get rid of the idea of "enterprise particularity", adhere to discipline before the law, and resolutely put discipline and rules ahead. Make full use of the patrol sword and audit sharp weapon, use the "four forms", increase serious accountability, keep a close eye on the new forms and trends of "four winds", persistently implement the spirit of the eight central regulations, and resolutely prevent the "four winds" issue from rebounding. Adhere to the "double investigation of one case", and seriously investigate the responsibility of the parties, the main responsibility and the supervision responsibility of the units and departments that have serious violations of discipline. Carry out centralized rectification to solve the problem of frequent violations at the grassroots level. We should make great efforts to catch early and catch small, strengthen warning education, educate people around us with cases around us, let party member cadres always feel the power of organization and supervision, awaken and strengthen the sense of discipline and rules of all party member cadres in the Group, and strictly implement various rules of honesty and self-discipline. Conduct a party discipline education throughout the system, integrate discipline education into business work, and penetrate into all aspects of business management. Make full use of the "Handbook of Integrity Education in the Whole Process of Hierarchical Classification" and the "Handbook of Integrity Practice Red Line" compiled and distributed, strengthen the education of professional ethics and industry norms, raise the awareness of risk prevention and integrity practice, and let the cadres and employees be alert, clear the bottom line and know awe.Consciously obey the rules and discipline, resist corruption and prevent change.

  (3) Strengthen institutional mechanisms and consolidate the results of inspection and rectification.

  2016 is the "year of comprehensive rectification" determined by the Party Committee of China People’s Insurance Group, mainly to comprehensively implement the rectification tasks such as the special inspection of the central government, the audit of the National Audit Office, and the "review" of the rectification of the "four winds" by the Central Commission for Discipline Inspection, so as to comprehensively rectify and consolidate the results of the inspection and rectification. We will persist in the efforts of rectification, do a good job in the continuous promotion and "looking back" of inspection and rectification, and earnestly consolidate and improve. Adhere to the combination of governing the party according to regulations and governing enterprises according to law, and continuously improve various rules and regulations. The established system, with process management, procedural provisions, information means to improve the effectiveness of the system, enhance the implementation of the system; If the system is not perfect, it should be problem-oriented, focusing on the root cause and prevention. Strengthen and improve the daily supervision and special inspection of system implementation, improve the accountability mechanism and enhance the authority of the system. With the help of the risk preference system, the economic capital model and the second phase of the risk basic data platform, through the implementation of the internal control system framework model, we will establish a thorough supervision mechanism, build an integrated comprehensive risk management system with people’s insurance characteristics, tie up and tighten the system cage including the construction of party style and clean government, standardize business behavior fundamentally, and consolidate the management foundation of the group.

  (D) Strengthen the ability to implement the strategy and serve the country’s economic and social development.

  During the "Twelfth Five-Year Plan" period, by strengthening the party building work and continuously consolidating the political advantages of the group, a new pattern of China People’s Insurance Group was formed to strengthen the leadership of the party and promote scientific development. Guided by the spirit of the series of important speeches by the Supreme Leader General Secretary, the Party Committee of China PICC Group will firmly establish the development concept of innovation, coordination, green, openness and sharing, scientifically plan and implement the Group’s "Thirteenth Five-Year Plan" development blueprint, strictly manage the Party in an all-round way, continue to promote customer-centered transformation, maintain steady growth, concentrate on reform and innovation, strengthen value creation, enhance professional ability, deepen transformation and development, and keep the risk bottom line. Firmly establish a big pattern thinking, give full play to the function of insurance, participate in, serve and promote economic and social development more firmly, and make new and greater contributions to building a well-off society in an all-round way.

  This special inspection tour of the Central Committee is of great significance to promoting the Party building and company development of PICC China Group. We will take this inspection and rectification as an opportunity, resolutely follow the requirements of the "five in one" overall layout and the "four comprehensive" strategic layout, earnestly shoulder the political responsibility of managing the party, earnestly strengthen the party’s leadership over enterprises, and promote the sustained and healthy development of the Group with tangible rectification results.

  Cadres and the masses are welcome to supervise the implementation of inspection and rectification. If you have any comments, please report them to us in time.

  Tel: 010— 62616611 to 2061

  Address: Supervision Department of PICC Group, No.28 Tsinghua West Road, Haidian District, Beijing.

  Postal code: 100084

  Email: jubao@picc.com.cn

  Committee of China People’s Insurance Group Co., Ltd.

  April 25, 2016

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Pentium pony strives to create a new life with smart driving, which one is more cost-effective?

Although cars can improve the convenience of people’s travel, safety is still an unavoidable topic. Therefore, many car companies have begun to upgrade the safety of their models. Of course, for consumers, a car with complete active and passive safety configurations will be more popular. The richness of a car configuration is related to the user’s car experience, so many people are concerned about its configuration today. Let’s take a look at it next.

First of all, from the appearance, the design style of Pentium pony head has taken a steady route, which is very sporty. Headlights are simple and fashionable, and the design is more fashionable and dynamic. The car is equipped with etc. Coming to the side of the car body, the size of the car body is 3000MM*1510MM*1630MM, and the car adopts simple lines, which gives people a very streamlined feeling. With large-sized thick-walled tires, the shape is eye-catching. In the design of the rear end, the overall shape of the rear end of the Pentium pony echoes the front face, and the taillights look very comfortable and have a rounded shape.

When I came to the Pentium pony car, the interior shape looked very simple and the overall shape was remarkable. The car looks very good outside the steering wheel, made of plastic, showing a sense of atmosphere. Take a look at the central control. The design of the center console is reasonable, which makes the interior style impressive and has a certain sense of science and technology. The dashboard and seats are equally eye-catching. The dashboard of the car presents a simple design style, highlighting the trendy temperament. The car uses fabric seats, which are wrapped in place and are basically enough for daily use.

Pentium pony matching gearbox, 30KW, 90N.m, good power performance.

The car is equipped with Bluetooth /WIFI connection, sunshade mirror, USB interface, uphill assist, rear reversing radar and other configurations, and the configuration performance is passable and basically satisfactory.

After reading the above introduction, let’s make a summary. Such a car with the right price is enough to meet the daily practical needs, and it doesn’t take much thought to maintain it at ordinary times, and the cost performance is good.

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Nakamura Shido dumped Meisa Kuroki and cohabited with a handsome white-collar woman.


Nakamura

    Nakamura Shido, a Japanese kabuki actor who has appeared in films such as Red Cliff one after another and is well known to China audiences, has recently been found to be madly in love with a female white-collar worker who graduated from Waseda University, even to the point of talking about marriage. According to FRIDAY, a photo magazine published on January 14th, 38-year-old Nakamura Shido was photographed buying a wedding ring with a 27-year-old female white-collar worker, thus speculating that Nakamura is about to enter the marriage hall for the second time.

    Nakamura Shido, who divorced actress YUUKO TAKEUCHI in 2008, has a son with his ex-wife, Takeuchi, who is now 5 years old. After the divorce, Nakamura was once rumored to be in love with 22-year-old Meisa Kuroki, but both denied it.

    According to the new issue of FRIDAY, the rumored girlfriend who is in contact with Nakamura has a short hair style, and the whole person looks particularly handsome. After graduating from Waseda University, she worked as a magazine graphic model during her school days, and became a white-collar worker of a silver jewelry brand company after graduation. On January 3, the magazine photographed Nakamura and the woman going to a jewelry store in Tokyo, and Nakamura chose a wedding ring for them. From their sweet smiles, it can be seen that they are by no means ordinary men and women. The magazine also revealed that Nakamura had started living together with this woman.

    According to relevant sources, Nakamura and this woman met through a friend’s introduction at an endorsement event in the summer of 2010, but the marriage was denied by this insider. "I don’t think it will be so soon … …” . After the divorce, Nakamura always avoided talking about emotional topics, but in recent interviews, Nakamura changed his previous avoidance attitude. When asked if he would get married within the year, Nakamura once said with a smile: "I will work hard!" The words reveal the expectation of remarriage.

[Movie Network]www.1905.com Exclusive manuscript, please indicate the source.

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Late-night construction also brings dust rolling? These problems that plague people’s lives have been …

Original title of this article: "Does the construction in the middle of the night bring dust rolling? These problems that plague citizens’ lives have been dealt with! 》

Dear friends,

The weekly [Echo] is coming again!

The mixer truck raises dust and the construction noise at night is loud?

Lack of road control, there are great security risks?

The school gate will be flooded whenever it rains, making it difficult to pass?

……

This week’s [Echo]

Continue to solve your problems!

reply

(No.39, 2018)

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01

User message content

Longxi Mountain, Gaoyao Country Garden, rushed to work day and night, and 2 tons of cars were forbidden to pass through this section. The mixer still shuttled through Cologne Street at 2 or 3 in the morning, raising a lot of dust, and did not sprinkle water on the road to reduce dust, which had a great impact on the life and travel of nearby residents. The dust was rolling during the day and the noise was constant at night. I hope the relevant departments would pay attention to it.

Gaoyao district Committee office

answer

After verification, netizens reported that the situation was true. The construction unit has implemented water spraying and dust removal, but the frequency is not enough, and the dust removal effect is not ideal.

On October 26th, a joint working group was formed by the departments of housing, construction, environmental protection, transportation and traffic police in our district. The person in charge of the Longxi Mountain construction project in Country Garden and the person in charge of the construction unit were interviewed, and the situation reflected by the netizens’ messages was reported to the person in charge. The project construction party was required to strictly abide by various rules and regulations to carry out construction and production according to law, reasonably arrange the construction time, and limit the impact of environmental pollution problems such as dust and noise on the surrounding residents to the greatest extent. It is strictly forbidden to overload and carry vehicles. That night, traffic, traffic police and other departments set up cards around "Country Garden Longxi Mountain" to enforce the law, and rectified the traffic violations of dump trucks, and the rectification action received certain results.

On October 27th, the working group formed a rectification plan on relevant issues as follows:

First, it is forbidden for the construction unit to carry out construction at night (from 22:00 pm to 6:00 am the next day), and the District Housing and Construction Bureau is responsible for supervision. If the construction at night is found, it will be ordered to stop work immediately for rectification.

Second, because the traffic of trucks over 2 tons is restricted in Cologne Street, construction vehicles must bypass the construction site through other roads to avoid dust and noise disturbing people, and the traffic police and transportation departments are responsible for supervision; The District Traffic Police Brigade carries out technical maintenance and upgrade of monitoring equipment in Cologne Street, and the District Transportation Bureau urges the owner to install weighing equipment at the cargo loading site and assign special personnel to manage it.

Third, the construction unit is required to increase the frequency of sprinkling water to reduce the dust on the road section, and the district environmental protection bureau is responsible for supervision.

In the next step, housing, construction, environmental protection, transportation and other departments will establish a linkage mechanism, strengthen joint law enforcement, conduct night inspections, and severely punish violations found. The traffic police department will implement the service system and increase the patrol monitoring of this section by setting up cards and taking irregular measures.

02

User message content

1. On the Hengda Haoting section of Dinghu 321 National Road, even if you can enter the auxiliary road after turning around from west to east, there is no municipal road that can turn into Hengda Haoting. Every day, many people from Duanzhou to Dinghu turn around here and then take the path next to the gas station to enter Hengda Haoting Road. Because it is not a municipal road, the road surface is not maintained and there is no safety control, which has great security risks. It is recommended to improve it!

2. Since the construction of National Highway 321, Xinyuan No.1 Street in Dinghu District has been flooded in every heavy rain, especially when typhoons such as Tiange and Mangosteen arrive, and even the flooding depth is more than 1 meter. The surrounding residents have repeatedly reported their problems to the petition offices and sub-district offices, but they have not received any reply or rectification.

Dinghu district Committee office

answer

(I) About the problem of netizens reflecting the section of Evergrande Haoting.

It is understood that the path that enters Taihe gas station after the U-turn of Hengda Haoting section of National Highway 321 is not a municipal road, but is owned by the gas station. The person in charge of the commercial gas station has no intention to maintain the path at present. Next, our district will strengthen the safety supervision around this section in conjunction with the traffic police department to ensure the travel safety of surrounding residents.

(2) About netizens reflecting the flooding problem in Xinyuan Street.

It is understood that due to the influence of Typhoon Mangosteen No.22 this year, from September 16 to 18, heavy rain continued to fall in our area, with local heavy rain, and the maximum rainfall recorded at Kengkou was 269 mm. Xinyuan First Street was one of the areas where flooding occurred.

During Typhoon Mangosteen, the rainfall lasted for a long time and was heavy, which greatly exceeded the design capacity of urban sewers and drainage standards, making it difficult to drain the rainwater on the pavement in a short time, and flooding occurred in many places in the area to varying degrees. Xinyuan 1st Street mentioned in the letter must be flooded in heavy rain after the construction of National Highway 321. The reason is that the elevation of the road surface has been improved after the urbanization of National Highway 321, which makes Xinyuan 1st Street relatively low-lying and prone to flooding.

In view of this situation, our district will speed up the construction progress of Xinshengtian Canal, complete the project construction as soon as possible under the premise of ensuring the quality, and strive to put it into use as soon as possible, so as to reduce the drainage pressure of urban sewers and reduce the flooding problem during the torrential rain in the district. In addition, the water department of our district has organized the construction team to comprehensively clear the municipal sewers of Xinyuan First Street and surrounding roads to ensure the smooth drainage of sewers in this area. In the next step, our district will refer to the vertical of surrounding roads and other factors, and appropriately adjust the ground elevation of Xinyuan Street to minimize the problem of road surface water accumulation.

03

User message content

1. The road at the gate of xinhua primary school will be flooded whenever it rains, and the water depth is more than 20 centimeters. Primary school students cannot pass after school, so parents need to carry it. I hope the relevant departments will go to the field to investigate and study solutions.

2. Two fans on the Blue Sky Water Gathering Building of Duanzhou Shanghai City Phase II roared for 24 hours. Standing on the balcony, I felt my ears tingle. I didn’t even dare to open the doors and windows at home. I couldn’t sleep when I opened the windows. I have reported to various departments that no one has handled them many times. Blue Sky Shuihui is a clubhouse, which is opened so close to the community. It is not legal at all. A few days ago, I heard the voice of singing K in the middle of the night.

Duanzhou district government office

answer

(1) About the problem that netizens report that the road at the entrance of xinhua primary school will be flooded when it rains.

According to the field investigation, xinhua primary school is located on the land on the east side of Xinghu Avenue and the north side of Donghu Road, which is lower than the municipal roads. The road at the entrance of xinhua primary school belongs to the village road, and drainage pipes and wells have not been built around it. The urban drainage network management center regularly cleans and maintains the municipal drainage pipelines of Xinghu Avenue and Donghu Road to keep the pipelines unblocked. However, due to the lack of supporting drainage facilities and municipal drainage pipelines around xinhua primary school, and the fact that it is located in a low-lying area, rainwater cannot be drained when it rains, so it is easy to form flooding in rainy days. Our district has urged Huanggang Sub-district Office to organize Fenggang West Village to do its best to do the pumping and drainage work of this section in rainy days, and dredge the drainage channels to reduce the impact of stagnant water.

As the north side of xinhua primary school is reserved land for the expansion of Honghu Lake, it will be built by the Municipal Construction Bureau. The next step in this area will be drainage planning and construction together with Honghu Lake, which is transferred to the east. After the drainage network in this area is improved, the flooding problem of the road at the entrance of xinhua primary school can be completely solved.

(B) About the problem that netizens reported that the noise of Shanghai Blue Sky Water Club Phase II disturbed people.

Upon investigation, the name of the place mentioned in the complaint is Duanzhou Blue Sky Holiday Leisure Center (hereinafter referred to as "Blue Sky Shuihui Club") registered in the administrative department for industry and commerce. Duanzhou Sub-bureau of City Comprehensive Law Enforcement Bureau received a report on the disturbance caused by the fan noise of Blue Sky Shuihui Club in early June. After repeated urging by law enforcement officers on June 8, July 11, July 17 and August 6, the club moved two fans on the roof that were originally close to residential buildings to the direction of the road, and connected the extended air ducts of the fans to the sound isolation box, which significantly reduced the noise.

According to the situation reflected by netizens, Duanzhou Branch of the Municipal Comprehensive Law Enforcement Bureau and the District Cultural and Sports Bureau sent law enforcement officers to the scene for mediation. On-site inspection found that in order to reduce noise and avoid noise spread, the club also closed the kitchen window. On the morning of October 10th, law enforcement officers contacted the relevant complainants by telephone to inform them of the handling situation and will monitor the noise of Blue Sky Holiday Leisure Center together with the municipal environmental monitoring station. The complainant expressed satisfaction and understanding of our work.

In the next step, our district will urge Duanzhou Branch of the Municipal Comprehensive Law Enforcement Bureau and the Municipal Environmental Monitoring Station to monitor the noise of the clubhouse as soon as possible, and follow up according to the monitoring report.

04

User message content

The industrial zone on the west side of Xiangang Toll Station often uses night time to secretly discharge harmful waste gas and smoke, which causes people living nearby to have difficulty breathing and seriously affects their health! We have repeatedly complained ineffectively, and now we question whether there is a problem with the efforts of the functional departments to implement the national environmental protection policy.

Gaoyao district government

answer

Recently, the environmental protection bureau of our district has received two complaints about the waste gas pollution in the industrial zone on the west side of the Xian Gang toll station, which the district environmental protection bureau attaches great importance to. Since the beginning of this year, in response to the problem of waste gas pollution in Xiangang Industrial Zone, the District Environmental Protection Bureau has repeatedly conducted surprise inspections with the People’s Government of Xiangang Town on enterprises in the industrial zone, and filed investigations on 14 enterprises with environmental violations, which severely cracked down on environmental violations of enterprises in the region. At the same time, since the creation of our district, the government of Xiangang Town has established a grid system, strengthened supervision and inspection of enterprises in the industrial zone, and required relevant enterprises to implement the environmental management system.

After receiving complaints from the masses, on the evening of October 10, 2018, the law enforcement officers of the District Environmental Protection Bureau, together with the staff of Gaoyao District Environmental Protection Monitoring Station and third-party testing institutions, went to the complaint area to conduct supervision and inspection, and sampled and monitored the ambient air at the northeast side (near the exit of the toll station), south side (in the junior middle school) and west side of the complaint area, and will focus on tracking and inspecting the enterprises near the relevant area according to the results of the ambient air monitoring report.

At the same time, the enterprises involved in waste gas emission and producing at night (Zhaoqing Gaoyao Hongzhan Hardware Plastic Co., Ltd., Chongqing Gaoyao Jinyi Aluminum Co., Ltd., Zhaoqing Gaoyao Zhaoxing Industry and Trade Co., Ltd., etc.) were monitored for waste gas. During the inspection, law enforcement officers found that the exhaust gas collection in the drawing and granulating workshop of Hongzhan Hardware & Plastic Co., Ltd. in Gaoyao District of Zhaoqing City was not perfect and the workshop was irritating, so they immediately asked the company to stop production and rectify. The next day, the district environmental protection bureau issued a notice to the company to stop production and rectify, requiring the company to resume production after the rectification is completed and reported to the bureau for inspection.

In the next step, the District Environmental Protection Bureau will continue to strengthen the supervision and inspection of gas-related enterprises in the industrial zone on the west side of the Xiaogang toll station, and intensify inspections. Once suspected environmental violations are found, they will be seriously investigated and dealt with according to law. At the same time, the district environmental protection monitoring station and third-party testing institutions are required to increase the frequency of spot checks and monitoring of gas-related enterprises near the complaint area, and investigate the enterprises suspected of exceeding the standard discharge according to law.

That’s all for this issue.

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Is cell therapy reliable in treating cancer? CAR-T leads the world, and 10 popular and emerging cellular immunotherapy show their magical powers!

The incidence of malignant tumor is increasing year by year, which has become a common problem faced by human beings. Traditional treatment methods such as surgery, traditional chemotherapy and radiotherapy have always played a leading role in cancer treatment, but the effects of these treatments are limited. In particular, it is difficult for advanced patients to benefit from these treatments for a long time, nor can they fundamentally solve or change their quality of life. Therefore, researchers are increasingly focusing on the field of immunotherapy. Immunotherapy has brought new opportunities and hopes for the treatment of tumors, among which Immunocheckpoint inhibitors, therapeutic antibodies, tumor vaccines, immunomodulators, adoptive cell therapy, etc. Significantly improved the prognosis of cancer patients, and some patients with advanced cancer obtained long-term survival. In the past two years, many cellular immunotherapy have emerged and developed rapidly, which undoubtedly set off a wave of cancer treatment. So, is cell therapy reliable in treating cancer? In fact, immunotherapy has a history of more than 100 years, and it has only gradually entered the public’s field of vision in the last two years, and it has been absolutely recognized by the world oncology community.   

20731650935352411   

A milestone in the history of cancer immunotherapy In 2013, Science magazine ranked the top ten scientific breakthroughs of the year, and immunotherapy topped the list. In recent years, immunotherapy is one of the hot spots in the research field of tumor treatment at home and abroad, and a large number of clinical studies have shown exciting results. Among them, Cellular immunotherapy uses the self-protection and killing ability of human immune system to achieve anti-tumor effect. Cells with immune function in patients are cultured and proliferated in vitro, and they are given the ability to attack tumor cells by technical means, and then they are imported into patients to realize their own anti-cancer. This therapyAgainst immune cells, not cancer cells.It is not as harmful to the patient’s health as surgery, radiotherapy and chemotherapy. Patients with early cancer can be treated directly, especially with the attack on residual cancer cells after surgery. Judging from the rapid development in scientific research and clinic in recent years, cellular immunotherapy is expected to become the fourth pillar of anticancer therapy in terms of accuracy, effectiveness and safety. Next, the small series of Cancer-free Home gives a general introduction and inventory of a variety of popular and emerging cellular immunotherapy in the biomedical industry, hoping to give cancer friends a general understanding of the general development process of this cancer treatment field. 

0one  CAR-T cell therapy

CAR-T therapy is chimeric antigen receptor T cell immunotherapy, which is a new precise targeted therapy for treating tumors. T cells are activated by genetic engineering technology, and the positioning navigation device CAR (tumor chimeric antigen receptor) is installed to transform the ordinary "warrior" of T cells into "super warrior" CAR-T cells, Specially identify tumor cells in vivo and kill tumor cells efficiently. So as to achieve the purpose of treating malignant tumors. At present, with 2021, Aquilencel injection, Regioscel injection. It was approved for listing in China, in 2022.Cedarchiorense was approved for listing by FDA.CAR-T therapy is expected to enter the blowout period. Indeed, CAR-T technology has shown good curative effect in many hematological tumors, such as leukemia, lymphoma and multiple myeloma, and more than half of hematologic cancer patients who are on the verge of despair and have no cure have achieved good curative effect.  

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CAR-T cell therapy has been listed at home and abroad at present.

Although the clinical effect of CAR-T therapy on solid tumors is not satisfactory, and it has even been sung down by some people, in recent years, CAR-T therapy has made outstanding progress in the fields of gastric cancer, liver cancer and pancreatic cancer. Scholars at home and abroad have made various modifications to CAR-T, and constantly found new targets for the treatment of various solid tumors.    

Clinical study on CAR-T therapy is out of the loop.

0one Gastric cancer and pancreatic cancer As the first CAR-T cell targeting Claudin18.2 in the world, CT041 emerged as early as the ASCO annual meeting in 2019. At that time, the total objective remission rate was 33.3%, which already surprised the world. Now the more remarkable curative effect is undoubtedly the icing on the cake! This clinical data shows a good treatment prospect for digestive system tumors!

Domestic CAR-T therapy CT041 first appeared in ESMO

Developed by Keji Pharmaceutical at the annual meeting of the European Society of Oncology (ESMO) in 2021.Targeting Claudin18.2(CLDN18.2)Autologous CAR-T candidate productsCT041Showing its presenceDigestive system tumorThe outstanding curative effect can be described as brilliant!

The research data is particularly eye-catching!

1. All patients’The objective remission rate was 48.6%, and the disease control rate was 73%.All patients with gastric cancerThe total objective remission rate was 57.1%.

2. Patients with gastric cancer who failed to receive at least 2 lines of treatment in the past:The objective remission rate was 61.1%, and the disease control rate was 83.3%.

3. And the overall tolerance is good!

As of March 3, 2022,CT041 became the first and only CAR-T cell candidate product in the world for the treatment of solid tumors, which entered the confirmatory phase II clinical trial.This is a milestone for CAR-T to conquer the solid tumor field. Congratulations!

In addition, there are many CAR-T cell therapies targeting CLDN18.2.0 2 liver cancer At present, the clinical trial targets of CAR-T in the treatment of liver cancer are mainlyGPC3 (phosphatidylinositol proteoglycan 3). The breakthrough research results completed by Professor Zhai Bo, director of the Department of Tumor Interventions, Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine, were published in the international authoritative journal Clinical Cancer Research on May 5, 2020. By July 24th, 2019, 13 patients had received CAR-GPC3 T cells with a median value of 19.9×108. All the patients are GPC3 positive, and they have received surgical treatment, local treatment or systemic treatment, and they all carry hepatitis B virus (HBV). Two patients achieved partial remission (PR). The 6-month, 1-year and 3-year survival rates of all patients were 50.3%, 42.0% and 10.5% respectively, and the median survival time (OS) was 278 days (39.7 weeks). At the ASCO annual meeting in 2021, Chinese medical researchers published the latest clinical research data of CAR-T drug targeting GPC3 (Ori-CAR-001) in the treatment of recurrent/refractory hepatocellular carcinoma for the first time. As of March 10, 2021, a total of 11 recurrent subjects who received cell infusion were included.All the subjects had advanced hepatocellular carcinoma, and none of them were effective after chemotherapy, TACE (transcatheter arterial chemoembolization) and targeted therapy.Of the 9 evaluable subjects,4 cases achieved partial remission (PR), 3 cases achieved disease stability (SD) and 2 cases developed disease progression (PD).The objective remission rate was 44%, and the disease control rate reached 78%.. 

02  Treatment of tumor infiltrating lymphocytes (TIL)

TILs therapy, simply speaking, is to separate and purify the lymphocytes in the tumor tissue after surgery, select the lymphocytes that can specifically resist cancer, and then amplify and activate them and reinfusion them. This kind of therapy has a history of more than 30 years, and it was first used for malignant melanoma. In recent years, it has given good data in many solid tumors such as cervical cancer and lung cancer.

This therapy is equivalent to pulling back veterans with combat experience directly from the battlefield. After a round of "political review" and "big competition" in professional ability, the spies and traitors are eliminated as far as possible, leaving the ones with the strongest fighting capacity, providing supplies, and then sending them back to the battlefield to continue fighting. Looking at the whole industry, the voice of "innovative therapy based on Tiles cells LN-144 (Lifelecel) is expected to be approved in 2022" is particularly loud. Tiles therapy, as an "ancient" cell therapy, is expected to usher in the first approved product this year, and its great potential in treating solid tumors can not be underestimated, with strong strength and relatively "out of the circle". TILs domain key node event     In 1982  

Steven A.Rosenberg and others discovered for the first time that TILs can inhibit the metastasis of melanoma cells in patients.

  1988  

The earliest attempt of TILs in clinical treatment: TILs therapy for metastatic melanoma achieved an objective remission rate of 60%.

  In 2011  

Steven A.Rosenberg and others published a phase II clinical research data in Clinical Cancer Research: the objective remission rate (ORR) and complete remission rate (CR) of patients with melanoma treated by TILs were 56% and 24% respectively.

  In 2012  

Melinda Bachini, a patient with advanced intrahepatic cholangiocarcinoma, is called the first patient to achieve complete remission (CR) after TILs therapy.

  2019  

At the ASCO meeting, the clinical results of innovative therapies LN-145 and LN-144(Lifileucel) based on TILS cells in the treatment of cervical cancer and melanoma have attracted wide attention in the medical field.FDA awarded LN-145 breakthrough therapy recognition.

  In 2021  

Phase I clinical results of TILs cell therapy at AACR meeting: among 12 evaluable patients.Non-small cell lung cancer patientsMedium,TIL therapy can achieve a total remission rate of 25%, among whichTwo patients achieved lasting complete remission.

  In 2021  

At the annual meeting of tumor immunotherapy association (SITC), the clinical research results of LN-145 in the treatment of metastatic non-small cell lung cancer (mNSCLC) showed that in 28 cases,In patients with recurrent/refractory mNSCLC,After LN-145 monotherapy,The overall remission rate (ORR) was 21.4%(1 case of CR and 5 cases of PR, including 2 cases of PD-L1 negative tumors), 12 cases were stable, and the disease control rate (DCR) was 64.3%.

03  TCR-T therapy

CAR-T cells and TCR-T cells belong to T cells modified by genetic engineering technology.Compared with CAR-T therapy, TCR-T therapy has unique advantages in the field of solid tumor treatment. TCR-T cell therapy can identify tumor-specific antigens from cell membrane surface or intracellular sources, and has entered clinical application from the initial basic immune research, showing initial efficacy in solid tumors, and has become the most likely T cell immunotherapy to make a breakthrough in the field of solid tumors! 

1、 TCR-T cell therapy in China has been approved for clinical use and has become a potential new therapy for HBV-related hepatocellular carcinoma!

At present, in addition to the global TCR-T in full swing in the research and development and clinical verification stage, China is also constantly breaking through innovation.

On December 22nd, 2021, CDE (Drug Evaluation Center) official website was able to inquire about the clinical application of "SCG101 Autologous T Cell Injection", which is a TCR-T cell therapy for specific hepatitis B virus (HBV) epitopes and a potential new therapy for HBV-related hepatocellular carcinoma (HCC).

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▲ Image source: CDE official website

2、 Advanced liver cancer ushered in a new dawn! TCR-T therapy makes cancer patients completely relieved.

As early as 2020 International Hepatology Conference (ILC), ADP-A2AFP, a new TCR-T therapy for liver cancer based on T cells, caused quite a stir, and also made a new breakthrough in the new therapy for liver cancer.

Among the included patients,One patient showed a complete remission (CR) in cancer progression, and the AFP of the other participants also decreased to varying degrees.This means that the experiment has made progress, and it also shows that this therapy is effective for the treatment of advanced liver cancer.

             

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All the 9 patients involved had undergone surgery and conventional radiotherapy and chemotherapy, but failed or became intolerant. Among the 4 patients who received the highest dose of treatment,One patient achieved complete remission, and CT scan showed that all the lesions in the patient disappeared, and it has lasted for more than half a year without any recurrence!

The best response of other patients (cohort 1, cohort 2) is stable. 1 patient in queue 2After one month of treatment, the volume of the primary lesion did not decrease, but the volume of mediastinal lymph node metastasis decreased obviously!       

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Therefore, TCR-T therapy targeting AFP (alpha-fetoprotein) can kill tumor cells expressing AFP. Based on the positive results of this study, researchers are expected to expand the maximum dose to 5 billion cells, and we look forward to the publication of updated data of this study!

04  CAR-NK therapy

In recent two years, in addition to CAR-T therapy, another new cancer cell therapy- Natural killer (NK) cell therapy It has also gradually attracted attention. The researchers said, NK cell As a cell anticancer therapy, it has more potential, and it may be safer, cheaper and faster. CAR-NK is to add a chimeric antibody to NK cells by genetic engineering that can recognize tumor cells and activate NK cells to kill tumor cells at the same time. 

one   The first "spot" CAR-NK clinical trial in China was approved by the Food and Drug Administration. On November 11, 2021, National Medical Products Administration Drug Evaluation Center passed an independent research and development in China. Mesothelin (MSLN) chimeric antigen receptor NK cells (CAR-NK) injection for the treatment of advanced epithelial ovarian cancer. Application for clinical trial of CAR-NK injection. According to the cancer-free home, This product is the first "spot" CAR-NK product of foreign origin in China. This also marks a new milestone in the research of immune cell drugs in the treatment of solid tumors in China! 

2  The 1-year survival rate doubled, and the curative effect of CAR-NK therapy in solid tumor increased sharply.

Recently, the journal Clinical Oncology Research published a phase II clinical trial for lung cancer. Heat shock protein 70(Hsp70) is highly expressed in about 70% of middle and advanced lung cancer. NK cells are activated by Hsp70 in vitro, which is equivalent to making NK cells meet their future enemies in vitro, "making enemies" first, and then returning them to patients, so that NK cells can formally fight with cancer cells in vivo. This method of stimulating NK cells with antigen peptides in vitro and giving them certain specificity is a hot topic in recent years.

A total of 16 patients with stage III non-small cell lung cancer were enrolled in this clinical trial. One group received traditional chemotherapy combined with radiotherapy and chemotherapy, and the other group received chemotherapy combined with Hsp70 pre-stimulated NK cell reinfusion.

The results show that:The one-year survival rate can be doubled from 33% to 67% by Hsp70 pre-stimulated NK cell reinfusion therapy combined with traditional radiotherapy and chemotherapy, and the preliminary results are encouraging.

Next, Xiaobian shows a typical successful case in combination therapy, as shown in the figure:After 1~2 months of treatment, the lung tumor completely disappeared and the curative effect has been maintained for 18 months.

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In addition to the above-mentioned clinical studies at home and abroad, CAR-NK cells also have a good effect on glioblastoma and neuroblastoma, specifically recognizing and killing breast cancer cells with high efficiency, and have a remarkable effect on multiple myeloma.

05  Dendritic cell vaccine

Cancer vaccine is a form of immunotherapy, which can prevent cancer from developing or kill existing tumors by stimulating or restoring the human immune system. Dendritic cell (DC) vaccine is a new biological therapy for malignant tumor in recent years, which has been paid more and more attention and recognized by oncologists. As an important member of the human immune defense system, Dendritic cells have the strongest antigen presenting function and are known as "sentinels" of the immune system. It is named because its cells extend outward with many dendritic protrusions. It mainly uses modern high-tech biotechnology to collect the peripheral blood of tumor patients, induce and cultivate a large number of dendritic cells in a short time in vitro, and equip them with immune cells that patients do not have, so as to accurately "target" and kill cancer cells. Not only that, It can also induce immune memory in patients, so that patients can obtain long-term anti-cancer effect.

DCVAC/LuCa is a dendritic cell vaccine developed by the United States for patients with non-small cell lung cancer.In a study on the first-line treatment of advanced lung cancer announced at the ASCO conference in 2019, DCVAC/LuCa vaccine combined with chemotherapy groupThe objective remission rate is 45%,The median overall survival time was 15.5 months, and the median progression-free survival time was 6.74 months.Reduce the risk of death by 46%!

In the Phase II clinical study of the latest novel dendritic cell vaccine DCVAC/LuCa (lung cancer dendritic cell vaccine) combined with standard carboplatin/pemetrexed in the treatment of advanced non-squamous cell (nsq) non-small cell lung cancer in 2022,The 1-year survival rate was 72.73% and the 2-year survival rate was 52.57%.By the time the data was published, the median overall survival time had not been reached. The median progression-free survival time was 8.0 months, and the objective remission rate was 31.82%.

  Prostate cancer-Provenge vaccine  

Provenge is the first vaccine approved for treatment in the United States, which initiated a new era of cancer immunotherapy.This is an autologous cell immunotherapy, which was approved by FDA on April 29, 2010 to treat asymptomatic or mild mCRPC. This approval marks the success of 20 years of unremitting efforts.In the United States, Provenge is the only FDA-approved immunotherapy for prostate cancer made from patients’ own immune cells.

  Ovarian cancer-dcvac/ovca vaccine  

At the 50th annual meeting of the Society of Gynecological Oncology (SGO) in 2019, the final result of SOV02, a phase II clinical trial, was announced: DCVAC/OvCa, an immunotherapy based on dendritic cells, was added to standard carboplatin and gemcitabine schemes for patients with recurrent, platinum-sensitive and epithelial ovarian cancer.It can prolong the overall survival (OS) of patients with advanced recurrent ovarian cancer by more than one year.andDCVAC/OvCa reduced the death risk of second-line treatment of ovarian cancer by 62%. The overall survival (OS) increased significantly by 13.4 months. The median progression-free survival rate (mPFS) increased by 1.8 months. The global phase III study will be launched soon.

Melanoma-TLPLDC vaccine

The subgroup analysis results of the phase IIb clinical trial of TLPLDC vaccine in the treatment of melanoma were published at the ASCO-SITC Clinical Immunooncology Conference in 2020.

In that population analysis follow the clinical research protocol (PT), compared with the comfort unit,The 24-month disease-free survival rate in TLPLDC treatment group was significantly improved (62.9% vs 34.8%), indicating that the relative risk of disease recurrence was reduced by nearly 50%.

In the population analysis of Intentional Treatment (ITT),There was no significant improvement in 24-month disease-free survival between TLPLDC treatment group and placebo group (38.5%) vs 27%),But in this analysis,The improvement trend of 24-month overall survival rate (OS) was stronger (86.4% vs 75.1%)..

  Kidney Cancer-Ilixadencel Vaccine  

Ilixadencel is an allogeneic dendritic cell (DC) vaccine. Research shows that,Ilixadencel combined with targeted anticancer drug sunitinib(Sotan, common name: sunitinib)First-line treatment of newly diagnosed advanced metastatic renal cell carcinoma(mRCC)Compared with patients treated with sunitinib alone, the total remission rate is doubled, the complete remission rate is higher and the remission is more lasting!

  Glioblastoma-AV-GBM-1 vaccine   On June 8, 2021, well-known foreign biomedical companies announced the release of phase II clinical trial data of their personalized cancer vaccine AV-GBM-1. The research shows that this new vaccine has great potential for prolonging the overall survival of newly diagnosed glioblastoma patients in the medium term. The median progression-free survival time of patients was 10.4 months, which was about 50% higher than the median progression-free survival time of 6.9 months in the landmark STUPP study, and established a nursing standard for newly diagnosed glioblastoma patients.     Non-small cell lung cancer-tedopi vaccine  

On April 1st, 2020, a new anti-cancer vaccine, TEDPI, achieved positive results in the phase III clinical trial of non-small cell lung cancer. After the immune checkpoint inhibitor (PD-1) was resistant or failed, all patients in the group used TEDPI vaccine in the second or third line, and the overall survival rate for one year reached 46%, far exceeding the preset 25%!

A 54-year-old patient with advanced lung cancer has rapidly shrunk (from 39mm to 23mm) after five injections of the new lung cancer vaccine. At the time of reporting, his survival time has exceeded 20.6 months, and he is still being followed up.

06  CIK cell therapy

  CIK cells, that is, Cytokine-Induced Killer (CIK), are a new type of immunocompetent cells, which have strong proliferative ability and cytotoxicity, and have certain immune characteristics. Because this cell expresses both CD3 and CD56 membrane protein molecules, it is also called NK cell (natural killer cell)-like T lymphocyte, which has both the strong anti-tumor activity of T lymphocyte and the non-MHC-limited anti-tumor advantage of NK cell. If NK cells are the "first line of defense" to protect human health, then CIK cells are undoubtedly the "precision missiles" to kill tumor cells. Especially for patients after surgery or radiotherapy and chemotherapy, it can eliminate residual tiny metastatic lesions, prevent cancer cells from spreading and recurring, and improve immunity. Therefore, CIK cells are considered as the first choice for a new generation of adoptive cellular immunotherapy for tumors. Research progress of representative CIK cell therapy     

nasal pharyngeal cancer  

Among 137 patients with nasopharyngeal carcinoma treated by CIK, 50% of them improved their survival time by 6-9 months, and among 137 patients treated by CIK, 50% of them delayed their tumor progression by 6-7 months.

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  liver cancer  

Among the 819 patients with liver cancer treated by CIK, 50% of them improved their survival time by 13~25 months, and among the 819 patients treated by CIK, 50% of them delayed their tumor progression by 4~7 months.

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  ovarian cancer  

Among 72 patients with ovarian cancer treated by CIK, 50% of them have improved their survival time by 24 months. Among 72 cases of ovarian cancer treated by CIK, 50% of ovarian cancer patients delayed their tumor progression by 14.5 months.

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carcinoma of colon

Among 126 patients with colon cancer treated by CIK, 50% of them have a longer survival time of 30 months. Among 126 patients with colon cancer treated by CIK, 50% of them delayed their tumor progression by 14.5 months.

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  breast cancer  

The probability that the survival time of 150 breast cancer patients treated with CIK can reach 5 years is increased to 85.7%; The probability of keeping breast cancer from recurring in 150 breast cancer patients treated with CIK within 5 years increased to 72.3%.88231650935357798

  Solid tumor  

Of the 31 patients treated with PD-1 antibody combined with DC-CIK, 2 patients’ tumors completely subsided and 5 patients’ tumors partially subsided. Of the above 7 patients, 6 patients’ effects can be maintained for 5 months. The tumors of the other 13 patients remained stable.

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  renal carcinoma  

Among 43 patients with advanced renal cell carcinoma treated by CIK, 50% of them can delay the tumor progression to 14.7 months.

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07  CAR-M therapy 

In recent years, the study of macrophages has also been paid attention to by the industry. How to activate the anti-tumor activity of these macrophages is the direction that immunologists have been working hard. CD47, an immune checkpoint on macrophages, has become a very promising hot target in the field of tumor immunotherapy.

In a recent study published in Nature Biotechnology, researchers from perelman Medical College of the University of Pennsylvania and other research institutions may have an alternative to T cell therapy to overcome these challenges. Their research shows that genetic modification of macrophages (an immune cell that devours intruders in vivo) may be the key to developing effective cell therapy for solid tumors. They were able to confirm these genetically modified expressions. The macrophages of CAR (CAR-M) can kill tumors in human samples and mouse models in the laboratory and prolong their life.   

81441650935359696   

CAR-M therapy is centered on macrophages, which devour invading cells instead of destroying them like T cells. T cells are more like Space Invaders games, while macrophages are more like Pac-Man games. Another major difference between macrophages and T cells is that they are the first responders of the body to virus infection. Historically, this poses a challenge in trying to genetically modify them to attack cancer, because macrophages are not easily transfected by standard viral vectors used in gene therapy and cell therapy.

In this experiment, the research team used genetic engineering technology to transform macrophages. They not only expressed CAR targeting HER2 antigen, but also were activated and differentiated into M1 macrophage types that promoted inflammation. In this way,These CAR-M cells can not only target tumor cells, but also change the microenvironment near tumors by secreting pro-inflammatory cytokines. They can also present tumor antigens to T cells and activate T cells’ immune response to tumors, which can be described as "killing three birds with one stone".

On March 18th, 2021, Carisma Company of the United States announced the completion of the first drug delivery to the subjects of CAR-M therapy (CT-0508) targeting Her2, marking a new era of CAR-M transformation therapy for solid tumors. In a word, taking macrophages as effector cells transformed by CAR is expected to reverse the tumor inhibitory microenvironment, so as to break through the obstacles of immune cell therapy in solid tumors. 

08  CTL (cytotoxic T lymphocyte) therapy

What cell therapy can be used as an adjuvant therapy for the majority of patients with inoperable advanced cancer? In recent years, researchers have been developing new immunotherapy schemes for these patients, including CTL(cytotoxic T lymphocytes) technology. This technology mainly uses protein, which is unique to cancer cells and has no or low content in normal cells, as bait to select the truly anticancer lymphocytes in peripheral blood, and then further improve and amplify them in vitro, and then return them to patients. MTCA-CTL immunotherapy is a new generation of biological immunotherapy model introduced in China. While ensuring the expansion of non-MHC-restricted killer NK-T cells, directional expansion of HC-restricted CD8++specific CTL cells can make its proportion in cell products reach 60% ~ 70%. The combined effect of this killer cell makes the efficiency of killing tumor cells higher.  

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At present, the multi-target compound antigen peptide biological immunotherapy technology, which is undergoing the second phase of clinical trials in the Cancer Hospital of China Academy of Medical Sciences, is the fifth and brand-new generation of cellular immunotherapy technology, which can optimize the activation method of DC (dendritic cells) to enhance the killing effect of immune cells on tumor cells. At present, it has achieved good clinical results and I believe it will really benefit cancer patients.

Mainly suitable for solid tumors.Head and neck tumor, esophageal cancer, lung cancer, gastric cancer, breast cancer, liver cancer, membranous adenocarcinoma, colorectal cancer, ovarian cancer, uterine cancer, coma cancer, prostate cancer, malignant melanoma, sarcoma and partial malignant lymphoma.

If economic conditions permit and you want to consult MTCA-CTL therapy, you can contact.Cancer-free Home Medical Department (400-626-9916), a detailed assessment of the condition.

09  CAR-NKT therapy

  Natural killer T cells (NKT) are a group of special T cell subsets that express both T cell receptors (TCR) and NK cell receptors on the cell surface, and can produce a large number of cytokines. Such as IL-4 and INFγ. These cells can not only directly dissolve and kill tumor cells, but also play an anti-tumor role through indirect ways (secreted cytokines, activated immune cells, etc.). Recently, a phase I clinical trial jointly conducted by Baylor Medical College in Houston and Texas Children’s Hospital is evaluating a new treatment for children with recurrent neuroblastoma –CAR-NKT cell therapy is expected to break through this bottleneck. Phase I trial, code-named GINAKIT2, used CAR-NKT cells for the first time to treat recurrent neuroblastoma. Eleven children (1~21 years old, with an average age of 7 years old) were all recurrent/refractory high-risk neuroblastoma, with extensive metastasis and no better treatment plan in clinic. The results are very encouraging: Of the 11 advanced patients, The condition of 4 patients was stable, 2 patients achieved partial remission (tumor was obviously reduced), and one of them had complete remission (CR) after receiving the second CAR-NKT cell infusion. In safety, CAR-NKT is safer than CAR-T therapy. No dose-limiting toxicity was observed in the first 28 days after infusion. 

10  Compound immune cell therapy

This technology will alsoSix kinds of cells, such as γδT cells, NK cells, NKT cells, killer T cells, dendritic cells and helper T cells.Activate, multiply 10 million to 20 million cells to 2 billion to 5 billion cells, and then inject them into patients. Cultivating such important immune cells at the same time greatly improves the therapeutic effect compared with single treatment.

Except for some leukemia and malignant lymphoma,It can be used for the treatment of most cancers, and has a good effect in refractory cancer types and advanced cancers. Besides,Compound immune cells also play a great role in improving immunity and strengthening the body.

Xiaobian has something to say

In recent years, due to the development of medical level, new cancer treatment methods have appeared one after another, among which cellular immunotherapy is in full swing, which brings new hope to cancer patients. According to the latest statistics, compared with patients with advanced lung cancer, gastric cancer and liver cancer who only receive surgery, radiotherapy and chemotherapy, adjuvant cellular immunotherapy can prolong the survival time of patients and significantly improve the data effect. In fact, tumor treatment is actually a complex "project", and it is difficult to achieve good results by relying solely on a certain treatment method. Tumor treatment needs the cooperation of various treatment methods to achieve the final victory in the fight against cancer. 

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Resume: Luxinshe

  Lu Xinshe, male, Han nationality, born in November 1956 in Juye, Shandong Province, joined the Communist Party of China (CPC) in July 1985, and joined the work in August 1982. He graduated from Wuhan Institute of Water Resources and Electric Power with a bachelor’s degree in irrigation and water conservancy engineering, and is an engineer.

  1978— In 1982, he studied in the Department of Farmland Water Conservancy Engineering of Wuhan University of Water Resources and Electric Power.

  1982— In 1986, cadres of the Land Administration Bureau of the Ministry of Agriculture, Animal Husbandry and Fisheries (during this period: November 1985.11— 1986.08 Studying at the German Training Center of Northwest Agricultural University, Ministry of Agriculture, Animal Husbandry and Fisheries)

  1986— 1990 Director and Deputy Director of the Comprehensive Registry of Cadastral Management Department of the State Bureau of Land Management (during the period: 1987— In 1988, the Federal Republic of Germany Hessian Survey Bureau and Hanover Cadastral Bureau studied; 1989.02— 1989.07 Central Party School, State Organs Branch)

  1990— 1992 Deputy Director, Cadastral Management Department, State Bureau of Land Management

  1992— 1996 Director, Cadastral Management Department, State Bureau of Land Management

  1996— 1998 Deputy Director of the State Bureau of Land Management and Member of the Party Group (1995— In 1996, he was appointed as the deputy mayor of Nantong City, Jiangsu Province)

  1998— 1999 Member of the Party Group of the Ministry of Land and Resources and Director of the Department of Cultivated Land Protection

  1999— In 2009, Deputy Minister of the Ministry of Land and Resources, member of the Party Group, Director of the State Bureau of Surveying and Mapping and Party Secretary (2005— 2008) (during this period: 2000.09— 2000.11 Central Party School Provincial and Ministerial Cadre Training Class)

  2009— In 2010, Deputy Minister of the Ministry of Land and Resources, Deputy Secretary of the Party Group, and Deputy Chief Inspector of State Land

  2010— 2011 Deputy Secretary of Gansu Provincial Party Committee and President of Party School of Gansu Provincial Party Committee

  2011— 2012 Deputy Secretary of Jiangxi Provincial Party Committee and Acting Governor

  2012— 2016 Deputy Secretary and Governor of Jiangxi Provincial Party Committee

  2016— 2018 Secretary of the Jiangxi Provincial Party Committee and Director of the Standing Committee of the Provincial People’s Congress (2017.01)

  2018— In 2019, Secretary of the Party Committee of Guangxi Zhuang Autonomous Region and First Secretary of the Party Committee of Guangxi Military Region (in April 2018)

  2019.01— Secretary of the Party Committee of Guangxi Zhuang Autonomous Region, Director of the Standing Committee of the People’s Congress of the Autonomous Region, and First Secretary of the Party Committee of Guangxi Military Region.

  Alternate member of the 17th Central Committee, member of the 18th and 19th Central Committees. Deputies to the 11th, 12th and 13th National People’s Congress. Member of the 11th Party Committee of Guangxi Zhuang Autonomous Region. Representative of the 13th National People’s Congress of Guangxi Zhuang Autonomous Region.

  (People’s Network information as of January 2019)

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How long does the rechargeable battery charge? Charging time of the rechargeable battery [Introduction]

  Abstract: Maybe everyone is very concerned about the battery, that is, how long should the battery be fully charged? This paper briefly explains that the calculation method of charging time of rechargeable battery is that the battery capacity is divided by the charging current, and then multiplied by the coefficient of 1.2 (or 1.1), and the time unit is hours.

  [Rechargeable battery charging] How long does the rechargeable battery charge? Charging time of the rechargeable battery.

  Charging time of rechargeable battery

  Maybe everyone is very concerned about the battery, that is, how long should the battery be fully charged? Many friends are worried that the lack of time and battery power may shorten the service life of the battery; If the time is too long, it may damage the phone and battery. So how long should it be charged? Here is a simple calculation method:

  Generally, the battery capacity is indicated on the battery, with mA as the unit. The larger the value, the greater the capacity.

  How long does it take to fully charge the battery? First, it depends on the nominal capacity of your battery. The larger the capacity, the longer it takes to charge. Second, it depends on how many batteries you charge at the same time. The charging time of two batteries is different from that of four batteries. Charging two batteries is twice as fast as charging four batteries. Third, it depends on the current that your charger can output. If the current is large, it will be fast, and if the current is small, it will be slow. Fourth, it depends on whether your battery is left. If it is completely dead, the charging time will be longer, and if there is still remaining power, the charging time will be shorter. There is a formula for charging Ni-MH battery: battery capacity (mA) ÷ charging current (mA) ×1.2~1.5= time (hours) required for the battery to be fully charged. Due to different chargers, the charging current is different. The charging time is generally indicated in the manual of the charger. It takes 10~20 hours for a full charge of four 2300mah batteries, 6~8 hours for a quick charge and 1~2 hours for a quick charge.

  Now all the better chargers have automatic detection function. When the battery is full, it will automatically stop charging. When it is charging, the battery is warm. After charging, it will cool after stopping for a while. The full indicator is different according to the charger, and some indicators flash when charging, and always light up when full; Some indicator lights are always on when charging, and the indicator lights go out after charging; Some indicator lights are red (or green) when charging, and turn green (or red) when full.

  Charging time of Ni-MH battery

  Calculation method of charging time of Ni-MH battery: the battery capacity is divided by the charging current, and then multiplied by the coefficient of 1.2 (or 1.1), and the time unit is hours.

  Steps/methods

  The battery capacity is divided by the charging current, and then multiplied by a factor of 1.2 (or 1.1) in hours.

  For example, if the capacity of a Ni-MH battery is 1200mA, the charging current of the charger is 600mA, and the charging time is (1200mA/600mA)×1.2=2.4 hours, then the charging time of this Ni-MH battery using this charger is 2.4 hours.

  The relationship between charging time and charging current of Ni-MH battery is that the battery capacity is divided by charging current to get the charging time. Considering the loss during charging, the calculated charging time is multiplied by the constant of 1.1 or 1.2.

  According to the logo, you can calculate an approximate time. If it is an ordinary charger and the current is small, the charging time must be very long.

  The above calculation method is not applicable to new batteries. Generally speaking, when new batteries are charged for the first three times, especially Ni-Cd batteries and Ni-MH batteries, the standard charging time is about 15 hours (0.1C), so as to maximize the service life of batteries. In the future, the battery charging time can be calculated with reference to the above method.

  How to calculate the charging time of rechargeable battery

  Generally, the battery capacity is indicated on the battery, with mA as the unit. The larger the value, the greater the capacity.

  For example, 1200mAh means that the battery capacity is 1200 mAh. At the same time, chargers are generally marked with charging current, also in milliamps.

  In this way, the charging time of the battery can be simply calculated as follows: the battery capacity is divided by the charging current, and then multiplied by the coefficient of 1.2 (or 1.1), and the time unit is hours. For example, if the battery capacity is 1200mA, the charging current of the charger is 600mA, and the charging time is (1200mA/600mA) × 1.2=2.4 hours, then the charging time of this battery using this charger is 2.4 hours.

  The above calculation method is not applicable to new batteries. Generally speaking, when new batteries are charged for the first three times, especially Ni-Cd batteries and Ni-MH batteries, the standard charging time is about 15 hours (0.1C), so as to maximize the service life of batteries. In the future, the battery charging time can be calculated with reference to the above method.

  What is the charging current indicated on the charger?

  I can give you a simple formula: charging and discharging time (minutes) = capacity *1.1/ current (mA) *60.

  The relationship between the battery charging time and the charging current is that the battery capacity is divided by the charging current to get the charging time. Considering the loss in the charging process, the calculated charging time is multiplied by the constant of 1.1 or 1.2.

  According to the logo, you can calculate an approximate time. If it is an ordinary charger and the current is small, the charging time must be very long.