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Global news： technology giants drag down US stocks collectively. Musk reveals new progress in brain-computer interface experiments.

　　On Tuesday (February 20th), Eastern Time, the first day after the market closed, the three major US stock indexes fell across the board, and the Nasdaq index fell more than 1% in intraday trading, closing at a two-week low. The dismal performance of the heavyweight technology giants and the market’s concern about the risk of the Fed’s potential return to raising interest rates are the main factors that weaken the market.

　　At the close, the Dow Jones index fell 0.17% to 38,563.80 points; The S&P 500 index fell 0.60% to 4,975.51 points; The Nasdaq Composite Index fell 0.92% to 15,630.78.

　　In terms of US debt, the benchmark 10-year US bond yield closed at 4.275%, and the 2-year US bond yield, which is most sensitive to the Fed’s policy interest rate, closed at 4.613%.

　　After the US stock market closes today, the market will welcome the financial report of AI leader NVIDIA, who is also the main contributor to the increase of US stocks this year. According to statistics, NVIDIA contributed a quarter of the increase of the S&P 500 index this year, and its financial report is likely to be a watershed in the trend of US stocks.

　　And because of its horrible rise and continuously high valuation, the market has begun to prompt risks. Some analysts believe that even if the company can hand over a slightly stronger than expected financial report, it is difficult to deserve its excessive valuation. Overnight, NVIDIA once fell more than 7% in intraday trading, and eventually it fell more than 4%, dragging down the market.

　　Bank of America analysts believe that it is not surprising that NVIDIA’s share price showed a "significant but short-term correction" after the financial report was released, given that investors had previously "blindly pursued artificial intelligence". The correction of the stock may exceed 10%.

　　Brent Kochuba, the founder of SpotGamma, thinks that once NVIDIA’s financial report is published, firstly, the implied volatility of the options market will decrease. The decline in implied volatility means that options will become cheaper, which will force market makers to sell some of their stocks to hedge their positions.

　　In particular, companies with large bias of call options like NVIDIA will bear greater selling pressure. In addition, due to NVIDIA’s current weight, it will detonate the "thunder" of the current "overheating" of the US stock market, and then cause a wider decline.

　　In addition, due to the high inflation in the United States, the market began to worry about the possibility of the Fed returning to raise interest rates. Last Friday, former US Treasury Secretary Summers said, "The possibility that the Fed will raise interest rates next still exists, and the probability may be 15%." More asset managers believe that the possibility is 20%.

　　In terms of industry, the first subject of Neuralink, Musk’s brain-computer interface company, is said to have realized the control of computer mouse through ideas. On Tuesday, local time, Musk said on the social media platform: "The patient seems to have fully recovered, without any adverse effects we know, and he can control the mouse. He can move the mouse on the screen just by thinking."

　　He also said that the company is currently trying to let patients "press the mouse button as much as possible through their minds", which includes moving the cursor up and down and dragging the box on the screen.

　　In terms of AI, Sora’s popularity has not yet fallen, and there is the fastest large-scale model explosion field in history. The AI chip company Groq became popular overnight, and the self-developed LPU speed crushed the NVIDIA GPU. Its text generation speed is faster than blink of an eye. The reasoning scene is 10 times faster than NVIDIA GPU, but the price and power consumption are only one tenth of the latter.

　　In addition, with the shortage of uranium supply and rising prices, uranium trading is becoming the hottest category on Wall Street, and both physical uranium and securities products are becoming very crowded. ETF, a uranium miner listed on NYSE, has increased by more than 55% in the past 12 months.

　　It is reported that investment banks including Goldman Sachs, McGree and some hedge funds are actively participating in uranium trading. Among them, Goldman Sachs not only involved in physical uranium trading, but also participated in option trading. Some hedge funds are also stepping up their participation in the trading of physical uranium and securities uranium products, which shows that after a decade of downturn after the Fukushima nuclear disaster, uranium trading has once again begun to shine and attract financial institutions to participate.

　　[Hot stocks]

　　Most large technology stocks fell, with Microsoft down 0.31% and Apple down 0.41%. Google rose by 0.31%. Amazon fell by 1.43%, NVIDIA by 4.35%, Meta by 0.33% and Tesla by 3.10%.

　　In terms of Chinese stocks, Nasdaq China Jinlong Index fell 1.33% to 6,005.10 points. Most popular Chinese stocks fell, with Xpeng Motors down 5.46%, JD.COM down 4.09%, Weilai and Pinduoduo down 2.93%, Baidu down 1.47%, Alibaba down 1.04% and LI up 0.57%.

　　[global index]

　　In the European stock market, the FTSE 100 index in Britain fell slightly by 0.12% to 7719 points. The French CAC40 index rose slightly by 0.34% to 7795 points. Germany DAX index fell slightly by 0.14% to 17,068 points. In Asian stock markets, the Hang Seng Index rose slightly by 0.57% to 16,248 points.

　　[foreign exchange commodities]

　　The main contract of Brent crude oil closed at $82.56 per barrel, down 1.20%; The main contract of crude oil in the previous period closed at 598.00 yuan per barrel overnight, down 1.01%. Overnight, the Shanghai gold main contract closed up 0.26% to 481.70 yuan per gram.

　　[Highlights]

　　Wall Street began to face up to the risk of the Fed returning to raising interest rates.

　　Last Friday, Lawrence Summers, the former US Treasury Secretary, broke the window and said something that some market participants thought but didn’t want to hear: "The possibility that the Fed will raise interest rates next still exists, and the probability may be 15%." More asset managers believe that the possibility is 20%.

　　Musk: The first human subject with brain-computer interface can control the mouse after rehabilitation thinking.

　　Musk revealed the latest progress of the first human subject of his brain-computer interface company Neuralink. On February 20th, Elon Musk, CEO of Tesla, revealed in a live broadcast of Spaces on social media platform X that the first human subject of Neuralink "seems to have fully recovered without any adverse reactions as we know. Subjects can move the mouse on the computer screen just by thinking. " Musk also said that Neuralink is now trying to get subjects to click as many mouse buttons as possible.

　　Groq, the fastest model bombing field in history, became a hit overnight.

　　Its self-developed LPU speed crushes NVIDIA GPU. NVIDIA’s challenger Groq appeared. Abandon GPU and develop LPU. Text generation is faster than blinking. The reasoning scene is 10 times faster than NVIDIA GPU, but the price and power consumption are only one tenth of the latter.

　　Microsoft is developing a replacement for the NVIDIA network card.

　　Microsoft is developing a new network card to improve the performance of its artificial intelligence chip Maia, and ultimately achieve the purpose of reducing dependence on NVIDIA products. Satya Nadella, CEO of Microsoft, has appointed Pradeep Sindhu, co-founder of Junbo Network, a communications equipment giant, to lead the network card project. The new network card that the Sindhu team aims to build this time is similar to the ConnectX-7 network card in NVIDIA, which is mainly used to improve the traffic speed of the server. According to the report, the development process may take more than one year. If successful, it is expected to shorten the time required for OpenAI to train the model on the Microsoft server and reduce the cost of the training process.

　　Apple adjusts the leadership of the supervision team responsible for audio products.

　　Apple adjusts the leadership of the audio product supervision team, and Gary Geaves will resign as the team leader and be replaced by Ruchir Davé.

　　Uranium becomes the new hot deal on Wall Street.

　　With the shortage of uranium supply and rising prices, uranium trading is becoming the hottest category on Wall Street, and both physical uranium and securities products are becoming very crowded. ETF, a uranium miner listed on NYSE, has increased by more than 55% in the past 12 months.

　　Us house of representatives sets up AI task force

　　On Tuesday (February 20th) local time, Speaker of the US House of Representatives Mike Johnson and Democratic Party leader Hakim jeffries announced that the two parties had formed a special working group to discuss legislation to solve people’s concerns about artificial intelligence (AI).

　　Red Sea crisis reshapes global fuel trade pattern, Indian diesel turns to Asia.

　　Due to the continuous turmoil in the Red Sea, the increase in freight rates has made it more attractive for transportation companies and commodity traders to export their goods to Asian countries.

　　[financial calendar]

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Anyang, Henan Province： From September 7 to 9, some areas carried out full-time nucleic acid, and residents implemented home management in principle.

　　CCTV News:"Anyang Rong Media WeChat WeChat official account News, Anyang COVID-19 Epidemic Prevention and Control Headquarters Office issued a notice. According to the current epidemic situation, in order to actively screen risks, prevent the spread of the epidemic, and effectively protect the health and life safety of the broad masses of people, the COVID-19 Epidemic Prevention and Control Headquarters decided to carry out regional full-scale nucleic acid testing in the urban area and tangyin county, Anyang County from September 7 to September 9, 2022. The relevant matters are hereby notified as follows:

　　1. Scope of control and detection: Wenfeng District, Beiguan District, Yindu District, Long ‘an District, Anyang County and tangyin county.

　　Two, the city’s residents in accordance with the requirements of "inspection", complete 1 round of regional nucleic acid testing every day. Please pay close attention to the time of nucleic acid testing notified by the jurisdiction, participate in nucleic acid testing in an orderly manner in different periods and do personal protection, and return to your residence immediately after testing. Personnel in high-risk areas, home isolation and home health monitoring shall be subject to relevant prevention and control regulations.

　　Three, since 16: 00 on September 7th, all residents at home in principle, non residents of the community (village) shall not enter in principle. In rural areas, the entry and exit of personnel are strictly controlled, and outsiders must report. There is no clustering or gathering in the community. Residents who go out for medical treatment and have other special needs may, with the consent of the community (village) where they live, "point-to-point" access to the community (village). Citizens (volunteers) who undertake epidemic prevention tasks, urban basic operation guarantee, medical security tasks and epidemic prevention tasks in the city can enter and leave the community (village) with the certificate issued by the unit (community, village) or work permit +24-hour negative proof of nucleic acid detection. The rest of the staff are all at home. Citizens who do not have to leave the country unless they have special needs can leave the country only with negative nucleic acid test certificate and community (village) certificate within 24 hours, and only after passing the inspection at the epidemic prevention checkpoint.

　　4. Since 16: 00 on September 7, public service enterprises such as water, electricity, fuel, gas, communications, sanitation, grain, oil, meat and vegetables supply that guarantee citizens’ lives and the basic operation of the city have arranged necessary personnel to guarantee public services; Industrial enterprises undertaking important production tasks implement closed-loop management; Life supermarkets (including farmers’ markets), medical institutions, pharmacies, express delivery, take-out and catering enterprises (only express take-out service is provided for restaurant meals) and railway operators that guarantee the basic needs of citizens can operate normally, while other entertainment and leisure places and "Nine Small Stores" are closed.

　　5. Suspension of public transport such as bus, taxi and passenger transport. Logistics transport vehicles such as industrial chain and supply chain, which come from low-risk areas, can directly reach their destinations through epidemic prevention bayonet with negative nucleic acid detection certificate within 48 hours; From the middle and high risk area, with the negative proof of nucleic acid test within 48 hours, people do not get off the bus and leave the window, "point-to-point" to the destination, and quickly leave Anyang jurisdiction after unloading without contact.

　　Six, the district (county) Party committees and governments, townships (towns, streets) and communities (villages) to establish a special team, timely service to protect the needs of the public, especially to do a good job of caring for special groups such as elderly people living alone, disabled people, pregnant women and so on.

　　This notice will be implemented from 16: 00 on September 7, 2022, tentatively for 3 days, and will be dynamically adjusted according to the progress of the epidemic and the needs of prevention and control.

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A swimming competition was held in a once polluted river in Shanghai, and officials from the Environmental Protection Bureau also took part.

On the afternoon of July 30th, an environmental protection riverside swimming competition was held in Chuansha Town, Pudong New Area, Shanghai, and more than 110 Shanghai residents competed to get into the water.

Through the application of the "zero discharge system for all-water reuse", the river channel that originally discharged domestic sewage from the factory has become a clear water river bank, which not only realizes zero discharge to the municipal sewage pipe network, but also allows the public to relive the childhood fun of swimming in the river.

On the afternoon of July 30th, an environmental protection riverside swimming competition was held in Chuansha Town, Pudong New Area, Shanghai. More than 110 Shanghai residents rushed into the water, and even two officials of the Pudong New Area Environmental Protection Bureau "couldn’t resist the temptation" and jumped into the river to complete the 80-meter race. Yao Haiyang, a 26-year-old boy who climbed ashore from the end of the river, said several "unexpected" words to The Paper (www.thepaper.cn). He said that he didn’t expect to swim in the river in Shanghai, and he didn’t expect his childhood memories of playing with water to be relived in Shanghai.

Riverbanks that discharge domestic sewage become clear water swimming lanes.

The natural river course for this swimming competition is 100 meters long, 8-10 meters wide and 2.2 meters deep. At one end of the river course is the starting platform covered with red carpet, and 80 meters away is the finish line made of red and white buoys.

At the competition site, a sign of "River Water Quality Test Conclusion" just issued by the environmental protection department on July 30th this year was hung in front of the departure platform: CMA authorities certified by the state sampled and tested the water quality and hygiene indicators of the river water, such as chromaticity, turbidity, pH value and total coliform. The test results showed that the measured water quality indicators met the Class I standard of surface water in the National Environmental Quality Standard for Surface Water GB3838-2002, and reached the national standard at the same time.

"Many people are asking me how you came up with the idea of hosting the Riverside Swimming Competition and how you achieved this goal. In fact, it originated from the dream of a 6-year-old boy ten years ago." Qu jianguo, chairman of Shanghai Kaineng Environmental Protection Equipment Co., Ltd., told The Paper a short story.

Ten years ago, a German customer and his son came to visit Kaineng Environmental Protection Park the day before returning home. qu jianguo showed them around the factory in the park and asked his six-year-old son, who was accompanying him, what he wanted in China? The child pointed to a river bank more than 100 meters long in the factory and blurted out, "I hope I can swim in this river bank." At that time, everyone was speechless. Looking at the disappointment of the German boy, qu jianguo promised: "When you come to China again in a few years, my uncle will definitely let you swim in this river."

Qu jianguo told The Paper that although he lost contact with this German friend later, this promise has been buried in his heart. After years of management and efforts, the natural river in this factory finally reached the surface water environmental protection standard for swimming in the river. The first Kaineng Environmental Protection River Swimming Competition came into being in the summer of 2013, and it lasted for four years.

How to achieve it technically?

A wish is a wish, but how can an ordinary natural river originating from Pudong New Area be transformed into a "clear river bank" with crystal clear water quality reaching the municipal first-class water?

"Thirty years ago, I caught up with the era of swimming in Qingshui River, but I never saw it again." Qu jianguo told The Paper that in 2012, they took the lead in launching the application of "Zero Discharge System for Water Reuse" in the environmental protection park in Chuansha. Simply put, it is to establish two sewage treatment stations in the east and north of the environmental protection park to realize full automatic control. The sewage from each unit in the park flows into the sewage treatment station through the sewage collection pipe network, and then undergoes anaerobic and aerobic degradation by microorganisms, so that the sewage reaches the treatment and discharge standards and enters the next constructed wetland ecosystem.

In the Kaineng Environmental Protection Park in Chuansha, large and small constructed wetlands and emergent plants form a unique green landscape, and there are many small sewage treatment systems hidden in the park. The water in the river swimming track is obtained from the recycling treatment of sewage, all of which is the ecological reuse of wastewater, and the environmental protection park has realized zero discharge to the municipal sewage pipe network.

“The treatment capacity of this zero-emission system can reach 100 tons/day, which is equivalent to the treatment capacity of 100 household water purification equipment. As far as technology is concerned, the system can be applied in southern China, and the difficulty of popularization mainly depends on the degree of government support and the source of funds."qu jianguo said.

Despite this, it is still not easy for the public to regain confidence in the river. Qu jianguo admitted that in 2013, when the swimming competition was held in the riverside of the factory for the first time, he took his 6-year-old grandson to jump into the river first to dispel people’s concerns about the safety and health of the river. In the first competition, only more than 30 swimmers participated in the end. With the improvement of everyone’s confidence, there are more than 100 swimmers participating in this year. "Many parents take the initiative to bring their children who are practicing swimming, let them play in the river lane and feel the joy of their parents when they were young."

Two deputy directors of Pudong New Area Environmental Protection Bureau (first from left and third from left) personally entered the river to participate in the competition.

Environmental protection officials also went into the river.

On the 30th, many people at the scene said that another signal that reassured them about the water quality was that two officials from the Environmental Protection Bureau of Pudong New Area also entered the river.

Liang Ming, the 57-year-old deputy director of the Environmental Protection Department of the Environmental Protection Bureau of Pudong New Area, signed up for the Youth Group, and won the third place in the group. He admitted to The Paper that it was "not easy" to have such a clean river bank in Pudong New Area. After all, most of the natural rivers in Shanghai still belong to Grade 5 water quality. From this perspective, the task of river bank regulation is "a long way to go".

Han Haibin, deputy director of Shanghai Pudong New Area Environmental Protection and City Appearance Sanitation Administration, revealed in an interview that, on the whole, the surface water quality of Pudong New Area ranks second in the whole city, and Chuanyang River, Zhangjiabang River and heqing town River, which have been vigorously regulated, have begun to reach Class III water quality. The natural rivers in Pudong New Area have reversed from 60% of the original water quality failing to meet the standard to 71.8% of the rivers meeting the requirements of surface water functional zoning in June this year. "After the renovation of Zhangjiabang, the water quality has been greatly improved, showing the great changes of smelly water bang, Qingshui River and landscape river, and it has become the first ecological landscape river in Shanghai. It is estimated that by 2020, there will be more and more rivers like Zhangjiabang and Kaineng Park. "

However, there is still an essential difference between river regulation and swimming in the river. Qu jianguo said, for example, the water quality of Suzhou River has bid farewell to the black smell and reappeared the clean water after vigorous rectification, but the dragon boat race is ok, and swimming in the river is still not up to the requirements. "In addition to the complexity of the river water body and potential safety hazards, whether the water quality of the river source can meet the national drinking water standard is also one of the decisive factors. Only when the water quality in the river reaches the level where rice can be washed and vegetables washed directly as in the past, swimming in the river can be called safe for human health."

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The courier has arrived! Thank you, the most familiar stranger express brother.

1905 movie network news In this special period, we saw many heroes who fought in the front line, but we often ignored the "unknown heroes" around us who have been providing assistance to us in the rear.

　

In this group of "unsung heroes", we have to mention the courier who is closely related to everyone. They have been escorting our lives, rain or shine, whether during our stay at home or at present when we have gradually resumed work.

　

On March 9th, Li Jie, a courier, attended the the State Council conference and said that the biggest difficulty now is that some communities are not allowed to enter, resulting in too little express delivery. He called for allowing couriers to enter the community on the premise of ensuring the health of couriers, so as to improve work efficiency.


Not to mention the "double 11" every year, they have to face all kinds of "explosive positions", and even the film industry can’t do without their "fastest support".


Everyone remembers the "sudden release" event in Better Days, but many people ignore that it is also because of the strength of this group of people that we can see the film smoothly on the day of the release.

　


The figure of courier brother can not only be seen everywhere in our lives, but also the art comes from life. Last year’s hit tribute drama "In the Distance" is an urban entrepreneurial drama that rarely focuses on the domestic courier industry. It allows us to see the development process of private express delivery enterprises, and they have all achieved today’s achievements through hard work.

　

In addition to this drama focusing on private express delivery in China, they are also the most indispensable roles in many movies.

　

Sorry, we missed you


In European and American countries, whenever a courier cannot reach the recipient, the courier will leave a note — — "sorry,we missed you" (sorry, we missed you).


Therefore, the famous British director ken loach made a film "Sorry, we missed you" with this sentence.

　

In this film, this sentence is not only a sincere apology at work, but also an apology for the children as a father in this family of the film.

　

In the film, my father is a courier. Every day, due to overwork, he can’t take care of the big and small things at home. He shoulders the burden of family economy and is bent on providing a stable life for his family, no longer looking at the landlord’s face and owning a house of his own. We can see that the courier is a profession he lives, and his real identity is the head of the family, the husband of his wife, and the father of his children.

　

At the end of the movie, although the hero lost his job, he didn’t play with his children as in the past, but still went out to work for a living. But this time, he said "sorry" to his family.

　

The rest of my life on a desert island


The film starring Tom Hanks is naturally a film that everyone is familiar with.

　

Chuck, the hero, works for FedEx, and he is as precious as gold on weekdays. A plane crash left him stranded on a desert island, far away from the hustle and bustle of the city, and opened up a new lifestyle. His belief in survival was supported only by the pocket watch and a courier package given to him by his fiancee.

　

Over the past four years, needless to say, his hardships and sufferings have turned into failures many times. When his will gradually collapsed, he was unexpectedly saved.


But when he returned to the real civilized world, he became nothing, and unlike fairy tales, his fiancee would wait for him all the time. Strong Chuck chose the blessing and stuck to his duty as an employee of the courier company, delivering the last package before the crash.

　

What exactly is this unopened express parcel? This is the curiosity that the audience outside the film are concerned about. But whatever it is, for him, it is a hope on a desert island and a sense of professional mission.

　

Two seconds


Courier is a race against time.

　

In the movie Two Seconds, the heroine Laurie is the kind of person who focuses on a simple and happy life. As a cyclist, she has no utilitarian heart, just reveling in this sport, enjoying the speed of chasing and eager to freeze the time. After retiring, she still chose the job of bicycle courier. To this end, she even devoted herself to her only racing car.


The life of a courier will not always be as fresh as it was at the beginning and only enjoy riding a bike. Riding a bike is not difficult for Laurie. She is handy, but she has to bear many unexpected difficulties and injuries at work.

　

Just like every courier, they all love their jobs, but they still encounter some unpleasant things when they rush about in crowded cities every day, either coldly or misunderstood, but because of this love, they all live hard and actively.

　

Of course, when we talk about choosing movies in the express delivery industry because we love bicycles, we have to recommend them again.


The hero turned to be a courier because he failed in stock trading, which led to bankruptcy. Compared with the drama of "Two Seconds", this film pays more attention to realism, which is the kind of freedom for couriers to shuttle through big cities and see the good scenery of a city.

　

Premium rush.


The same bicycle courier is even more thrilling.


The hero met a tricky thing, and was entrusted to send an unknown letter. Unexpectedly, it attracted the eyes of a policeman in new york, which led to a series of chasing stories.

　

This film gives an account of the life of express mail, and adds persistence to their fun of riding a bicycle. Express delivery people are happy, persistent, love their work and enjoy the exciting life face to face with time. They are flesh and blood, love and hate, not all of them are poor at the bottom, but some of them come from university campuses, such as the protagonist and his girlfriend.


Probably like the couriers in our life, although they are service industries, they have the responsibility of being full of goods, and they can enjoy their own philosophy of life only by making a phone call to get them to the consignee faster and better.

　

《Life express


The movie "Hard Courier" is also a story about the courier being passively involved in a gang plot.

　

Jason Statham plays a retired special soldier, and now he is engaged in driving a BMW to transport goods. Unexpectedly, in a mission, he accidentally found that the goods he was transporting turned out to be a person. He started a magical adventure in line with the "three rules" in the industry.

　

For couriers in life, the "three rules" mentioned in the film are also the professional rules they pay attention to every day: 1. Never change the agreement; 2. Don’t mention your name; 3. Never open the package.


Because of this spirit of contract, on weekdays, the courier and we have more trust and tacit understanding with each other.

　

Super express


In the movie, when the courier played by Michael Chen met his future mother-in-law, he expressed that he would become "the best courier in China" in the future, and he also published a long declaration:

　

"The most important concept of China’s economy in the Internet age is O2O! What is the most important part of O2O? It is logistics! What is the main component of logistics? It’s us couriers! Without couriers, there will be no cheap and good goods; Without commodities, there is no consumption power; Without consumption power, there will be no future of the real economy. Therefore, it is our ordinary couriers who have set up a day in China’s economy! "

　

This slogan may be the voice of the staff in the express delivery industry.

　

In addition to these films, couriers, as the "most familiar strangers" in our lives, often appear in different films and become the strongest supporting actors.


Perhaps the appearance of these walk-ons is only for better advertising, but we may expect that in the future movie market, there will be works belonging to this group of people, and we can also use movies to tell them, "Thank you, courier brother."


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The American Democracy Foundation funded 50 China projects to support anti-China forces.

　　A "non-governmental organization" solely funded by Congress.


　　Everyone in the United States emphasizes its status as a "non-governmental organization", but as long as we understand its funding source and organizational structure, we know that the Democratic Foundation is actually a US government department in the cloak of "non-governmental".


　　The practice of promoting "American-style democracy" in a hidden way originated after the end of World War II. In order to prevent communist party’s influence from expanding in Europe, American policymakers began to subsidize pro-Western media and political parties in the form of secretly sending consultants, equipment and funds. By the end of 1960s, some American "private groups" began to receive secret funds from the CIA, which were also used to weaken communist party’s influence. These "private groups" later grew into "American Political Foundation", which is the predecessor of American Democracy Foundation.


　　In November 1983, US President Ronald Reagan ordered the establishment of the American Democracy Foundation, and asked Congress to allocate $65 million for "promoting global democracy" in the fiscal year of 1984-1985. In addition to funding from Congress, the board structure of the American Democracy Foundation makes this "non-governmental organization" even more weird, because its members include two members of Congress, officials of American labor, business and education institutions, foreign policy experts, and representatives of Republicans and Democrats. John Richardson, the first "permanent chairman" of the Democracy Foundation, was a former assistant secretary of state. The current chairman, Carl Jeshman, was a senior adviser to the Permanent Representative of the United States to the United Nations.


　　The Democratic Foundation initially sought funding of $31.3 million a year, but Congress only gave it $18 million. Even so, some opponents of the Democratic Foundation in Congress suggested to the White House that since the Democratic Foundation is "non-governmental", it should not be appropriated by the US Congress, but should absorb donations from the people. However, the US Congress still insists that all the funds of the Democracy Foundation are allocated by the Congress, and it has repeatedly intervened in the projects of the Democracy Foundation, often giving it "specific guidance". For example, the US Congress asked the Democracy Foundation to support solidarity trade unions in Poland and "special interest groups" in Chile, Nicaragua and Eastern Europe. The US Congress also asked the Democracy Foundation to "give special support" to relevant organizations in South Africa, Myanmar, China, (China) Tibet and North Korea. After the "9.11" incident, the Democracy Foundation threw out the third strategic document and began to sponsor a large number of projects in Middle Eastern countries.


　　At the same time, the amount of funds allocated by the US Congress to the Democracy Foundation is actually increasing: from the initial "quota" of $33 million to $40 million in 2004, and then jumped to $60 million in fiscal year 2006. In fiscal year 2008, the annual appropriation of the American Democracy Foundation was $100 million.


　　It is the executor of American strategic intention.


　　The American Democracy Foundation is very good at bringing together various "democracy foundations" in western countries to do their work. For example, in order to promote the democratic process in Myanmar, the American Democracy Foundation has brought together the Westminster Democracy Foundation in Britain, the Conrad Foundation in Germany and the International Center for Human Rights and Democratic Progress in Canada, and contributed to the "Democratic Forces in Myanmar". When dealing with China, North Korea and other Asian countries, the American Democracy Foundation mainly draws on Japanese, Italian and Portuguese "Democracy Foundations".


　　How does the American Democracy Foundation approve a project? An expert familiar with the operation of the Foundation told the Global Times reporter that there are two sets of audit procedures for the American Democracy Foundation: a clear set of procedures is published on the official website, such as quarterly discussion and evaluation by the Board of Directors of the Democracy Foundation, which comprehensively considers the priorities, specific needs, national conditions, democratic effects and related experiences of the project, and then grants money to groups or organizations. Applicants should fill in a series of forms, such as project details, expenditure, budget plan, name and position of the person in charge of the organization, etc. The China expert told the Global Times reporter, "Whether the American Democracy Foundation gives money or not is mainly based on the degree of influence of this project on the national interests of the United States, the destructiveness to relevant countries, and the degree of recognition of American-style democracy by relevant organizations or groups. In the final analysis, the interests of the United States are fundamental. If it is not in line with the national interests of the United States, it is difficult to get a penny from the Democracy Foundation. "


　　Kim A. Holmes, vice president of the Center for Foreign Affairs and National Defense Policy Studies of the United States, and Sherby Kurom, director of the Institute of International Relations of the Heritage Foundation of the United States, disclosed that on August 1, 1996, the Appropriations Committee of the United States Senate tried to cancel the funding of 30 million U.S. dollars to the Democracy Foundation that year, on the grounds that although the Democracy Foundation played an important role in "promoting democracy" in the Soviet Union, China, Cuba, Iran, Iraq, Nicaragua, Vietnam and other countries, the Cold War was after all. However, U.S. lawmakers who support continuing funding for the Democracy Foundation said that despite the disintegration of the Soviet Union, communist party remained in power in China, Cuba, North Korea and Viet Nam, and communist party’s influence in the former Soviet republics remained considerable, so communist party’s global power should not be underestimated. Lawmakers believe that governments under western-style democracy pose less threat to the interests of the United States. Because they pursue profits and are keen on business activities, they are more willing to maintain international stability. Democratic countries rarely go to war with democratic countries, so strengthening the promotion of democracy, such as investing in the American Democracy Foundation, is much less costly than going to war with an "undemocratic country", which is in the best interests of the United States. ▲　　

Editor: xu wen hua

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The 2017 Buick Angkewei officially went on sale for 209,900.

　 　 [XCAR new car listed original]

　　On September 19th, SAIC-GM announced that the 2017 Buick Angkewei was officially launched. In 2017, Angkewei added three models, namely, the 20T front-drive technology model, the 20T front-drive luxury model and the 28T four-wheel drive leading model. The whole lineup was expanded to 10 models, and the price range was 209,900-349,900 yuan.

　

　 　 After reading the main points, this article is half finished:

　 　 1.2017 Angkewei’s appearance/interior is the same as the current model, but the configuration is upgraded.

　 　 2. The new car is upgraded with Onstar car 4G LTE and a new generation of smart interconnection system supporting AppleCarPlay, and a new agate red appearance color scheme is introduced.

　 　 3. The new car comes standard with ABS+EBD+ESC+TCS system and HSA ramp auxiliary system.

　 　 4. Still equipped with 1.5T and 2.0T engines.

SAIC-GM Buick 2016 Angkewei

SAIC-GM Buick 2016 Angkewei

　 　 The appearance/interior of the 2017 Buick Angkewei is consistent with the current model. The new car is upgraded with Onstar’s in-vehicle 4G LTE and a new generation of smart interconnection system supporting AppleCarPlay, and a new agate red appearance color scheme is introduced to bring consumers more choices of models. In addition, the 2017 Angkewei also comes standard with a wealth of configurations: LED daytime running lights and taillights, keyless entry and one-button start, ANC active noise reduction technology, automatic engine start/stop, full LED ceiling lighting, EPB electronic parking, reversing radar, etc.

SAIC-GM Buick 2016 Angkewei

　 　 In terms of safety configuration, the new car comes standard with ten active safety configurations, including ABS+EBD+ESC+TCS system, HSA ramp auxiliary system, SLSC linear stability control system, BAS braking auxiliary system, CBC corner braking control system, EDC engine resistance moment control system and ROM rollover induction system. At the same time, it is equipped with ACC adaptive cruise, LKA lane keeping, FDI distance warning, FCA front collision warning, CMB collision mitigation and RCTA parking warning.

SAIC-GM Buick 2016 Angkewei

　 　 In terms of power, the new car is still equipped with 1.5T and 2.0T engines, with maximum power of 124kW and 191kW respectively and peak torque of 250Nm and 353Nm respectively. The transmission is matched with 7-speed dual clutch and 6-speed automatic manual transmission.

　 　 Editor’s comment:Recently, GM has upgraded its models one after another, and most of them are upgraded in configuration, and the cost performance is further improved, which is expected to continue Angkewei’s outstanding performance in sales.

Related content review:

Or sell 209,900 to expose the new Angkor real car/configuration.

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Test drive and experience China Zunchi 1.8T automatic manual integration (multiple pictures)

　　3.23 I received a phone call in the morning, and the new 1.8T Zunchi test drive car has arrived. I started a test drive at the weekend and invited old users to participate!


　　I didn’t have time to go on Saturday, but I went with my brother-in-law at 9 o’clock on Sunday morning! As soon as I entered the gate of the 4S shop, I saw a row of Junjie, and there was a red bracelet in the silver and blue hall, which was very attractive to female friends! It is estimated that the car came with 1.8T. The owner hasn’t had time to take it away, but only a black 1.8T Zunchi waited alone and looked around him first, which is roughly the same as what I saw on the Internet!



　　When I entered the hall, there was actually a new 1.8T car in it, next to the red Junjie mentioned just now. Because I just went to work, there were few people in the hall, only two salesmen, and I didn’t care to say hello to the two, so I sat in Zunchi directly. At this moment, one of the two came to ask me if I wanted to buy a car. I said I had already bought it, and I came to test drive, plugged in the key and ignited it. I felt that the engine was not loud and the direction was not right. It’s a bit astringent to put the D gear on, and the foot is lifted slightly. The car moves slowly, and the throttle feels better than the old car. The heavy body feels very relaxed. When you go out, turn left and go on a straight road. When the throttle is stepped down slightly, the car jumps out. When you are moving, you feel that the car is very stable, the brakes are still so reassuring, and the car is relatively quiet. The whole test drive process lasts about 10 minutes.


　　Disadvantages:


　　1. I am mainly dissatisfied with the interior, and those round air outlets are the first to bear the brunt.


　　2. The dashboard looks uncomfortable and I don’t like it.


　　3. The storage box of the co-pilot has poor texture.


　　4. The design of the front armrest is so poor that it seems to resist, including the big hole at the bottom of the center console.


　　5. The revision of the door lock was not very successful.


　　Advantages:


　　1. Strong motivation, needless to say.


　　2. The rearview mirror is much bigger and has a wider field of vision.


　　3. The direction, brakes and throttle are all lighter than before.








The appearance of China Zunchi 1.8T

> > Click to view more pictures.<<

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Scientifically grasp the connotation, characteristics and path of high-quality economic development

　　Theoretical connotation of high-quality economic development

　　The report of the 19th National Congress of the Communist Party of China pointed out that China’s economy has shifted from a high-speed growth stage to a high-quality development stage. This is a major judgment made by the CPC Central Committee with the Supreme Leader as the core according to the changes in the international and domestic environment, especially the changes in China’s development conditions and stages. The core of high-quality economic development is quality first and benefit first, which has profound theoretical connotation and great practical guiding significance.

　　Looking at the history of world economic development, the understanding of the law of economic development evolution and quality and efficiency is deepening with the development of social productive forces. From the early use of "efficiency" or "efficiency" to express the pursuit of the quality of economic development, to the economic growth theory in western economics that technological progress is the decisive factor to achieve sustainable economic development. With the deepening and development of theoretical research, the research on the quality of economic development has gradually expanded to institutional system, social equity, environmental protection and so on.

　　With regard to the current high-quality economic development in China, the central authorities stressed that high-quality development is a development that can well meet the people’s growing needs for a better life and embodies the new development concept. This thesis clarifies the purpose and means of high-quality development. Described by personal capital, high-quality economic development is an economic development that provides high-quality products and services to the whole society in a sustained and fair way with high efficiency and high efficiency, and it is a high-quality, high-efficiency and high-stability supply system in the specific economic form.

　　First, the quality of the supply system is high. The supply system includes three links: factor input, intermediate input and final output. The quality of the three links of the supply system is closely related. The high quality of the supply system means that the quality of all three links should be high. The high quality of factor input refers to the high quality of labor, capital, technology, energy resources, data, information and other factors put into the supply system, which is manifested in the high quality of labor, the high degree of automation, data and informatization of production materials, the high degree of greening of energy resources, the high technical level put into the production process, and the large scale, quality and value of information and data resources. The high quality of intermediate products means that the intermediate products in the production process, such as the quality and precision of parts, can meet the production needs well, which requires the continuous improvement of industrial division of labor and specialization, the continuous optimization and upgrading of industrial structure, and the formation of an effective collaborative and mutually supportive supply chain system. High quality of final output is an important connotation of high-quality development, that is, what we usually call high quality of products and services means that we can provide high-quality products and services to meet the diversified, personalized and escalating high-grade needs of consumers and better meet the growing needs of people for a better life. High-quality supply system is characterized by high quality and high performance of products and services at the level of specific output forms; At the industrial level, it is manifested as a rational and advanced industrial structure.

　　The second is the high efficiency of the supply system. From a static point of view, the high efficiency of the supply system is manifested in the unity of high technical efficiency and good economic benefits. Technical efficiency determines that under the given resource conditions, production possibility frontier, in the reality of scarce resources, promoting high-quality development inevitably requires the efficient and intensive development of the potential of existing resource elements, maximizing the input-output efficiency of various production factors, and achieving a fairly high level of capital efficiency and human resource efficiency. Economic benefits emphasize the rationality of resource allocation and combination, which represents the degree of allocation efficiency and reasonable distribution. High-quality development requires the rational allocation of resources between different uses, so that the marginal productivity of all kinds of factors can reach the highest, and marginal return of all kinds of factors can reach the highest. From a dynamic point of view, the high efficiency of the supply system is also manifested in the continuous improvement of efficiency, which has become the driving force for sustained and strong economic development, that is, economic growth has shifted from mainly relying on factor input to relying more on the improvement of total factor productivity, and the contribution of total factor productivity in the driving force of economic growth has been continuously improved. In this sense, the transformation process of economic growth momentum is also a process of promoting output efficiency, and power transformation and efficiency improvement are unified.

　　Third, the stability of the supply system is high. High-quality economic development should also be reflected in maintaining a relatively high level of stability in the supply system. From the time dimension, high stability is characterized by stable economic operation in a reasonable range in the short term and strong sustainability of output in the medium and long term. From the spatial dimension, high stability requires not only the health and stability of the economic system itself, but also the coordination of the economic system with society and environment. At the same time, economic development can provide development opportunities for all members of society, and the results will be shared by all people. In terms of resources and environment, rational utilization of natural resources and effective protection of ecological environment can bear long-term sustainable economic growth. In short, high stability of economic development means stable economic operation, controllable major risks, bearable resources and environment, and shared development achievements.

　　It should be emphasized that the high quality, efficiency and stability of the supply system are the core essence of high-quality economic development. Only when these characteristics are simultaneously possessed, and these characteristics are mutually supportive rather than conflicting, can they be called high-quality economic development.

　　High-quality development is a gradual and systematic development process

　　Summarizing the past development experience at home and abroad, high-quality development shows obvious stage characteristics. With the transformation of economic development stage, some aspects related to development quality, such as product and service quality, technical efficiency and economic benefit, economic growth power transformation, environmental quality, income distribution, etc., will change in trend at a certain time. It mainly shows that with the economic development, the quality of production factors such as capital and labor has been continuously improved, the quality of output has been continuously improved, the labor productivity has been continuously improved, and the industrial added value rate has been continuously improved. The driving force of economic development has shifted from factor-driven to efficiency-driven and innovation-driven, and the industrial structure has been continuously upgraded. What needs special attention is that these trend changes do not happen naturally, which are not only the embodiment of objective laws, but also the result of institutional policies.

　　By analyzing the changes of main quality indicators in different development stages, we can find that the transition to high-quality development presents the following typical characteristics: First, it is gradual. High-quality development is a process of constant change and slow evolution, and it is also a process from small accumulation to big change, from quantitative change to qualitative change. In this development process, factors, product and industrial quality, output efficiency, economic growth momentum, as well as the stability of economic growth and the sustainability of development have gradually changed. The improvement of output quality usually starts from the improvement of micro-factor quality, and then the driving force of economic growth shifts from factor-driven to efficiency-driven and innovation-driven. At the same time, the use efficiency of micro-factor and macro-total factor productivity are constantly improved, which lays the foundation for the improvement of output quality. The gradual development of high quality is also the result of the gradual improvement of demand level. The high quality of supply cannot exist in isolation from the fundamental purpose of meeting demand, and it needs to meet the low-level demand first and then change to meet the high-level demand. The second is systematic. High-quality development is an all-round and systematic process of change, and high-quality development in various fields is both a prerequisite and a result. In this development process, systematic changes have taken place at both ends of supply and demand, input and output, micro and macro fields. This includes both the optimization of industrial structure on the supply side and the upgrading and shifting of consumption on the demand side; It includes not only the improvement of labor, capital and other factors at the input end and the quality of intermediate inputs, but also the improvement of product quality and performance at the output end; Including the improvement of the use efficiency of micro-elements,It also includes the improvement of macro total factor productivity; It includes not only the transformation of short-term growth momentum, but also the fairer and more sustainable long-term development. What needs to be seen is that high-quality development is a spiral upward process, which is not only an objective and inevitable law that quantity accumulation will inevitably turn to quality improvement at a certain stage, but also the result of policy efforts to overcome difficulties and take the initiative. The two work together to better promote high-quality economic development.

　　An important path to promote high-quality economic development

　　Promoting quality change, efficiency change and power change of economic development is the key to realize high-quality economic development. Among them, quality change is the main body, efficiency change is the main line, and power change is the foundation. The three depend on each other and are an organic whole. Generally speaking, the core of promoting the three major changes is to improve the quality of factors and increase the total factor productivity, and the fundamental driving force lies in scientific and technological innovation and institutional innovation.

　　First, to improve the quality of the supply system as the main direction to promote quality change.

　　Improving the quality of the supply system is to promote the all-round reform of ideas, objectives, systems and work details in specific fields. It is a systematic project, and the quality reform should be promoted from three aspects: the quality of factor input, the quality of intermediate input and the quality of final output.

　　The first is to improve the quality of factor input. Factor input is the foundation, and its quality directly affects the quality of intermediate input and final output. From the perspective of labor factors, the higher the health status, years of education and skill level, the higher the output quality. From the perspective of capital factors, the output quality of different levels of factories, machinery and equipment will also be significantly different. From the perspective of technical factors, adopting higher-level science and technology and technology will also help to improve the quality of output. It can be said that the quality of factor input largely determines the quality of output and is the starting point for improving the quality of supply system. At the same time, recent studies show that the improvement of factor quality in developed countries has made an increasingly significant contribution to economic development, and the improvement of factor quality also has spillover effect on productivity improvement.

　　The second is to improve the input quality of intermediate products. The refinement and specialization of socialized division of labor constitute the industrial chain form of all walks of life. The quality of products in each chain will affect the quality of final output, and the input of intermediate products in key links can even directly determine whether the final output can be produced and the quality of production. China has been deeply embedded in the global industrial chain, but there are still many bottlenecks in the intermediate products of key links. Therefore, improving the input quality of intermediate products is the key to improve the quality of supply system, which requires building a mid-to high-end industrial structure and forming an effective industrial synergy supporting system.

　　The third is to improve the quality of final output. Starting from better meeting people’s growing needs for a better life, high quality products and services is the core and foothold of high quality supply system. The final product and service quality is related to the quality of residents’ consumption and the international competitiveness of a country’s products. We must speed up the improvement of China’s product and service quality by adjusting the quality standard system and promoting the quality brand action, so as to better promote the quality improvement of the supply system.

　　Second, promote efficiency change with improving total factor productivity as the core.

　　Improving output efficiency is the eternal theme of economics. The key to promoting efficiency change is to improve total factor productivity, so that economic growth depends more on total factor productivity. Total factor productivity is the "residual" contribution excluding the contribution of factor input. To improve the total factor productivity, we must vigorously promote the efficiency reform, constantly improve the technical efficiency and improve the efficiency of factor allocation.

　　The first is to improve technical efficiency. Technical efficiency corresponds to production possibility frontier, and improving technical efficiency means pushing production possibility frontier outward, which means the maximum output increase caused by the same scale of investment. From the essence of economic development, technical efficiency is the most important connotation of total factor productivity, and it should also occupy the most important position in total factor productivity, because it has broken through the original capacity boundary and reached a new and higher level. Promoting technical efficiency and continuously increasing the contribution of total factor productivity to economic growth is an important way to break the constraints of resources and environment and an important driving force to maintain long-term sustainable economic growth.

　　The second is to improve the efficiency of factor allocation. The efficiency of factor allocation affects the distance between actual output and production possibility frontier. If only the technical efficiency is improved and the factor allocation efficiency is low, the actual output will be far away from production possibility frontier, and the potential of technological progress to promote economic development will not be fully released. Under the dual economic structure, promoting the transfer of production factors from low-productivity departments to high-productivity departments and improving the allocation of factors have a significant effect on improving the total factor productivity. In addition, other factors that affect the efficiency of factor allocation include system and management. Good system and high-level management can also provide effective incentives, thus improving the supply and use efficiency of factors and improving the total factor productivity.

　　Third, focus on scientific and technological innovation and system reform to promote dynamic change.

　　From a deeper perspective, the driving force of economic development is to expand the input and output drive of existing resources and factors under the established technical level, which is an extension expansion on the original path. The other is to expand the scope of resources, improve the efficiency of resource elements and create new output drivers through technological and institutional innovation, which is a structural change of the economy. The change of the driving force of economic development, from relying mainly on the former to relying mainly on the latter, is an important manifestation of the economy turning to high-quality development.

　　First, scientific and technological innovation is the key driving force for economic development. Without technological innovation, with the increase of resource scarcity and the law of diminishing factor returns, economic development will come to a standstill. Through technological innovation, we can expand the scope of available resources and break the bottleneck of resources; Improve the use efficiency of resources and elements, and create more output with less input; It provides a technical basis for the configuration and combination of elements in a larger space; Create new diversified and high-quality products and services to better attract and meet the demand; Solve the negative effects of economic development on the environment and enhance the sustainability of economic development. It can be said that all aspects of the connotation of high-quality development are closely related to scientific and technological innovation, so scientific and technological innovation must be the first driving force for high-quality development.

　　Second, institutional innovation is also an important driving force to promote high-quality economic development. Institutional changes affect all dimensions of economic development. Reasonable institutional arrangements can continuously improve the quality and efficiency of economic development in a country or region, improve the total factor productivity and better promote high-quality economic development. For example, reasonable property right system and price system arrangement are helpful to promote the recombination of production factors, improve the efficiency of factor allocation, and are conducive to economic and efficient development; Effective market competition mechanism and intellectual property protection system can accelerate innovation and technological progress and promote economic innovation and development; Scientific management of resources and environment and system of ecological civilization can promote the improvement and sustainability of resources and environment; Wait. At present and in the future, we should make more efforts to deepen the reform of institutional mechanisms, so as to better stimulate the creativity and development vitality of the whole society and promote higher quality, more efficient, fairer and more sustainable economic development.

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No bid, no sales, no raw materials! How do pharmaceutical companies that are ＂holding their throats＂ survive？

No bid, no sales; There is no raw material in the bid. Can pharmaceutical companies with "involuntary fate" survive in the cracks?

Recently, Zhejiang Pharmaceutical Machinery Purchasing Center issued a notice on suspending the online trading of cefmetazole sodium for injection of Suzhou Dongrui Pharmaceutical Co., Ltd. (hereinafter referred to as Dongrui Pharmaceutical).

Description of the announcement: The cefmetazole sodium for injection produced by Suzhou Dongrui Pharmaceutical Co., Ltd. failed to fulfill the obligation of selecting the first batch of drugs in our province, and said that the raw materials of cefmetazole sodium for injection could not be purchased and the normal supply of the drug could not be guaranteed. After research, the online trading of cefmetazole sodium for injection (specifications: 0.5g and 1.0g) produced by Suzhou Dongrui Pharmaceutical Co., Ltd. will be suspended from now on.

According to the description in the announcement, the reason why Dongrui Pharmaceutical fulfilled the obligation of winning the bid was related to the inability to purchase raw materials.

01 or withdraw from the network due to the supply of raw materials.

In November, 2020, Zhejiang Medical Machinery Procurement Center issued the Procurement Document for Centralized Procurement of Some Drugs in Zhejiang Province, announcing that eight drugs, such as Rabeprazole Oral Constant Release Dosage, Ursodeoxycholic Acid Oral Constant Release Dosage and Cefemetazole Injection, will be purchased with quantity, and the procurement cycle will be 12 months. Among them, the agreed purchase quantity of cefmetazole injection (specification 1.0g) is 2,502,800 pieces.

In January this year, Zhejiang Medical Machinery Purchasing Center announced the results of the selection, involving 10 varieties. According to the principle of winning the bid in Zhejiang Province, if there are more than two bidding enterprises, the lowest quotation will be selected, and only one enterprise can be selected. Dongrui Pharmaceutical beat 17 other competitors, such as Harbin Pharmaceutical Group, Fuan Qingyutang, Beite Pharmaceutical, etc. The company’s cefmetazole sodium for injection (powder injection, packaging specification: 1.0g/ bottle) was selected by 8.2 yuan. The successful result will be implemented from March 15th.

However, on April 14th, Zhejiang Pharmaceutical Machinery Purchasing Center released another report on the purchasing results of cefmetazole sodium injection. According to the circular, because Dongrui Pharmaceutical refused to fulfill its bid-winning obligations, it did not complete the work of signing the purchase and sale agreement and establishing the distribution relationship, which affected the normal implementation of the bid-winning results. As for the lack of cefmetazole sodium in centralized drugs due to Dongrui Pharmaceutical’s failure to fulfill the obligation of selection, the processing method of Zhejiang Medical Machinery Purchasing Center is that the purchase of cefmetazole sodium injection with quantity is treated as no selected product, and all medical and health institutions temporarily purchase it according to the original method.

Dongrui Pharmaceutical may also be defended for failing to fulfill its obligations as required and causing losses to medical and health institutions.

For enterprises with dishonesty, Zhejiang Medical Equipment Purchasing Center has also implemented notification measures while reminding medical and health institutions to choose carefully and avoid purchasing products from untrustworthy enterprises.

When pharmaceutical companies participate in centralized procurement declaration, they will be required to provide the Commitment Letter of Drug Declaration Enterprise. Among them, it includes the requirement of credibility: there is no serious illegal record in the two years before the declaration, such as disturbing the order of centralized procurement, maliciously violating the contract and other acts contrary to honesty and credit. The requirement for production capacity is that the annual production capacity of the declared varieties should reach 2 times or more of the agreed purchase quantity. If it is untrue, it is willing to accept the treatment including canceling the qualification for winning the bid and including bad records.

Under normal circumstances, the punishment result of the successful company’s failure to fulfill the obligation of successful selection will be more serious, while the punishment result of Dongrui Pharmaceutical this time is notification, which is relatively light. This result may be related to the inability of Dongrui Pharmaceutical to purchase APIs.

According to the company’s official website, Dongrui Pharmaceutical is mainly engaged in the development, manufacture and sales of cephalosporin antibiotics and system specialized drugs. According to the information of domestic drugs in National Medical Products Administration, there are currently 28 pharmaceutical companies in China with a total of 65 registered production approvals of Cefmetazole Sodium for Injection. Suzhou Dongrui has registered production approval documents of 1.0g and 0.5g cefmetazole sodium for injection.

According to media reports, it was learned from interviews with several regional sales leaders of Suzhou Dongrui that raw materials could not be purchased because the upstream raw material enterprises were unwilling to supply Suzhou Dongrui. "At first, we were told to raise prices substantially, but we accepted it. But then the manufacturer said that it could not be supplied. " Informed employees of the company revealed.

In China, only six pharmaceutical companies, including Harbin Pharmaceutical Group, Fuan Pharmaceutical Group, Chongqing Bosheng Pharmaceutical and Chongqing Gisrui Pharmaceutical, have registered production approval documents for cefmetazole sodium raw materials.

According to Health Network, in February this year, the price of rare varieties of cephalosporin raw materials doubled, and the most concerned small product was cefmetazole sodium raw material. The recent price increase was caused by the price increase of raw materials and the lack of manufacturers. The original price of domestic manufacturers was about 4,000 yuan /kg, and now it is quoted at 8,000 yuan /kg.

The supply cut-off incident of Dongrui Pharmaceutical further highlights the "dilemma" faced by pharmaceutical companies whose raw materials are not in their own hands: if a large number of raw materials are hoarded before the election, but the results are not selected, the pharmaceutical companies will face the risk of unsalable products and broken capital chains at any time; If you don’t hoard a large number of APIs, but the result is selected, you will face the current problem of Dongrui Pharmaceutical, "you can’t buy APIs with money", which will eventually lead to the suspension of drug supply.

02 API monopoly, who is controlling it?

Since the procurement with quantity was carried out at the end of 2018, the supply interruption of selected products has occurred from time to time.

In 2019, the supply of Fosinopril sodium tablets of Bristol-Myers Squibb (BMS) was cut off due to insufficient supply, which became the first cut-off event after centralized procurement, and was finally supplemented by Huahai Pharmaceutical. At the end of last year, two selected products, Penglai Nuokang Pharmaceutical Metformin Tablets and Nanjing Changao Pharmaceutical Pivastatin Calcium Tablets, were unable to be supplied in sufficient quantities in a short period of time, so the transition period was increased by three months.

There are many reasons for drug supply interruption, and the shortage and price increase of raw materials are very important factors. In recent years, many API companies have also been issued "sky-high fines" for alleged monopoly.

At the beginning of this month, Tianyao Co., Ltd. was punished by Tianjin Municipal Market Supervision and Management Committee for allegedly reaching a monopoly agreement on fluoxetine bulk drug, with a fine of 44.02 million yuan.

In April, 2020, the State Administration of Market Supervision made an administrative penalty decision on the illegal acts of abusing the dominant market position of three calcium gluconate raw material drug distribution enterprises, namely Shandong Kanghui Medicine, Weifang Taiyangshen Medicine and Weifang Puyunhui Medicine, and confiscated a total of 325.5 million yuan. This is also the biggest fine for the monopoly of APIs since the implementation of the Anti-Monopoly Law.

In November 2020, Wanbangde Pharmaceutical was fined 2.474 million yuan for abusing its dominant market position and attaching unreasonable trading conditions to the production and sale of bromhexine hydrochloride.

According to the Annual Report on Anti-monopoly Law Enforcement in China (2019) issued by the State Administration of Market Supervision at the end of 2020, there were 6 monopoly cases in the API industry in 2019. According to incomplete statistics, since 2016, a total of 15 companies, including Tianyao Co., Ltd., have been subject to administrative penalties for monopolistic behavior of APIs.

Why monopoly events frequently occur in the field of APIs?

There may be "passive" and "active" reasons for this.

"More registered pieces, less actual production". China holds 8482 valid API approval documents, and there are 1699 pharmaceutical companies with API production license qualifications. However, there are few companies that can actually produce and actually produce.

According to the information released by the Price Supervision, Inspection and Anti-monopoly Bureau of the National Development and Reform Commission, there are about 1,500 kinds of APIs in China, but their production is in the hands of a few manufacturers, of which only one enterprise can produce 50 kinds of APIs, only two enterprises can produce 44 kinds of APIs and only three enterprises can produce 40 kinds of APIs. Some people in the industry have also analyzed that many enterprises are unwilling to produce low-priced drugs because of their low prices and low profits, which is more likely to lead to monopoly.

"Environmental protection costs are under great pressure". On January 1, 2018, the "Environmental Protection Tax Law" was officially implemented, and the collection of sewage charges was changed to the collection of environmental protection fees, which greatly increased the cost for API manufacturers that needed a large amount of sewage discharge. Raw material medicine enterprises urgently need to be upgraded, and in the process of upgrading, some enterprises closed down because they could not bear the cost of upgrading.

Only a few companies have the qualification for examination and approval and the production capacity. In addition, with the increase of costs, the number of API enterprises has further decreased, and the output has also been affected.

According to the data of the National Bureau of Statistics, since 2018, the output of APIs in China has experienced a cliff-like decline, from 3.478 million tons in 2017 to 2.823 million tons in 2018, and then to 2.621 million tons in 2019. In the case of "scarcity is precious", the price of raw materials has also soared. In 2018, the price of roxithromycin rose from 590 yuan/kg in May to 735 yuan/kg in October. The price of chlorpheniramine, commonly used in cold medicine, rose from 400 yuan /kg to 23,300 yuan /kg in just one month, up 58 times.

In view of the "passive" monopoly of API enterprises, Wu Huifang, the general manager and chief researcher of Health Network, has conducted an analysis before. "There are mainly two aspects: on the one hand, the output is not large, although there are some approval numbers for APIs, there are few manufacturers that can actually produce them normally, and the size of preparation manufacturers is uneven. In this case, the price increase of APIs is also a last resort; On the other hand, the monopoly of many APIs is not caused by the active behavior of API companies, but by the competitive means of preparation distributors, especially for preparation bidding, that is, the underwriting party forces competitors to make concessions in preparation bidding by controlling the supply of APIs. "

In addition to the "passive" factors, there are also many enterprises in the market who choose to "do it intentionally". According to insiders, some of the monopoly phenomena of APIs are due to human manipulation. One mode is to indirectly control several natural persons to acquire the approval documents, so that all the market of the API is assigned to its own "circle", and finally only one of them is allowed to produce, and the rest of the approval documents are idle, resulting in monopoly of the market, and then the price is raised. Another mode is to sign a "National General Underwriting Agreement" between a third-party commercial company and an API enterprise, so that all APIs can be brought together. If you want to buy APIs, you can only buy them through the channels provided by the company, but API enterprises can’t participate in the pricing, resulting in monopoly.

These models make it more difficult for the regulatory authorities to investigate and deal with monopoly events.

In addition, according to Article 47 of the Anti-Monopoly Law, "if an operator violates the provisions of this law and abuses the dominant position in the market, the anti-monopoly law enforcement agency shall order him to stop the illegal act, confiscate the illegal income and impose a fine of more than 1% and less than 10% of the sales in the previous year."

In the monopoly case of Tianyao shares, Tianyao shares were fined 4% of sales in 2019 and confiscated illegal income. The proportion of 4% is not high in recent years because of the monopoly of APIs. Previously, Kanghui Company, Puyunhui Company and Taiyangshen Company were fined 10%, 9% and 7% of the annual sales in 2018 respectively for the monopoly of calcium gluconate for API injection.

However, in terms of the amount, the 4% sales of Tianyao Co., Ltd. in 2019 corresponds to about 35.1247 million yuan, while the 9% sales of Puyunhui Company in 2018 are 48.3 million yuan, and the 7% sales of Helios Company in 2018 are 12.4 million yuan. After receiving the ticket, Tianyao Co., Ltd. lowered its estimated net profit in 2020 from the original "55 million yuan-75 million yuan" to "31 million yuan-37 million yuan", which is equivalent to a fine of nearly half of the net profit for one year.

Compared with the sales of 10% in the previous year, the price difference and huge profits brought by monopoly for several consecutive years will still make some companies choose to take risks, which is one of the reasons why the monopoly of APIs has been repeatedly banned.

How to deal with the downstream pharmaceutical enterprises

The monopoly of APIs is undoubtedly "strangled" for some downstream pharmaceutical companies. The price of raw materials is rising, and the price of centralized drugs is low. The profit margin of pharmaceutical enterprises is constantly being compressed and even the phenomenon of "price upside down" appears. Without profit margin, many pharmaceutical companies can’t give up drug production, which leads to the shortage and interruption of supply of commonly used drugs, which is extremely unfavorable to society and ordinary people.

Faced with the monopoly of APIs, the national regulatory authorities have been "striking hard" and cracking down on monopoly. And how should pharmaceutical companies in the downstream "save themselves"?

Wu Huifang said that in the market competition, the powerful preparation manufacturers left behind have sufficient purchasing power, and they are planned and do not owe debts; In addition, we can follow the procurement mode of pharmaceutical preparations, and pharmaceutical enterprises can jointly bid for the procurement of raw materials.

It is also reported that Dongrui Pharmaceutical, which withdrew from the network due to the interruption of the supply of raw materials, will build its own raw material drug production line in the future and "take its fate in its own hands".

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Ministry of Transport： Four measures to prevent and control the epidemic situation in Spring Festival travel rush and provide services.

　　People’s Daily Online, Beijing, January 30 (Reporter Lu Jing) On January 30, the joint prevention and control mechanism of the State Council held a press conference. Han Jinghua, Deputy Director of the Transport Services Department of the Ministry of Transport, attended the conference and answered questions from reporters.

　　This year, the passenger flow in Spring Festival travel rush has increased substantially. How can the Ministry of Transport do a good job in epidemic prevention and control and service? Han Jinghua introduced that there are four specific measures as follows:

　　The first is to formulate and implement epidemic prevention guidelines and refine the prevention and control measures of epidemic situation. According to the requirements of "Class B Management" and the characteristics of passenger flow in Spring Festival travel rush, the epidemic prevention and control guidelines for comprehensive transportation in Spring Festival travel rush and Covid-19 were formulated, and 14 epidemic prevention measures were defined in four aspects: disinfection and ventilation of stations and means of transport, protection of employees, publicity and guidance, and emergency response. Strengthen dispatch and supervision, guide all localities to strictly implement the requirements of the guidelines, disinfect and ventilate the passenger contact areas, facilities, equipment and means of transportation in the station, strengthen the health monitoring and protection of employees, and stop operations as soon as symptoms appear to ensure the safety of transportation and epidemic prevention.

　　The second is to optimize transportation service measures to minimize the risk of infection. Actively provide non-contact services such as online ticket purchase, e-ticket and self-service ticket inspection to reduce unnecessary personnel contact. Strengthen the passenger flow organization of passenger stations, guide the public to queue up in an orderly manner, disperse and wait for passengers, and reduce the concentration of people. Increase the input of transportation capacity during peak hours, operate "point-to-point" chartered cars and increase night buses according to the needs of the masses, strengthen the connection between different modes of transportation, improve the transportation service capacity, and reduce the gathering of people and long waiting. At the same time, some key passenger stations have also prepared necessary epidemic prevention materials such as antipyretics and thermometers to deal with emergencies.

　　The third is to organize supervision and inspection and implement the main responsibility of epidemic prevention and control. In order to implement the epidemic prevention measures of transportation, transportation departments at all levels have carried out various forms of comprehensive and special inspections. Before the Spring Festival, the Ministry of Transport, together with relevant departments, went to 13 provinces to carry out supervision and inspection, and urged transport operators to strictly implement epidemic prevention and control measures such as disinfection and ventilation of passenger stations and vehicles, transportation organization and personnel protection, and resolutely guard against the spread of the epidemic through transportation.

　　The fourth is to strengthen epidemic prevention propaganda and guide the masses to travel rationally at the wrong peak. Make full use of service guarantee windows such as "cars, boats, airplanes, roads, ports and stations" and media channels such as television, radio and internet, strengthen epidemic prevention propaganda, release travel information in time, guide the public to travel rationally and avoid peaks, remind passengers to avoid taking public transport when they are sick, wear masks regularly throughout the trip, actively reduce gathering, and be the first person responsible for their own health.

　　In addition, Han Jinghua stressed that at present, it is at the peak of returning after the holiday, reminding the majority of passengers that in order to be safe and healthy, they should wear masks all the way in the process of entering and leaving the passenger station and taking public transportation, and work together to prevent and control the traffic epidemic.

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